AAOS Orthopedic MCQs (Set 1): Neurofibromatosis & Genetic Syndromes | 2026 Board Review

Key Takeaway
This high-yield question set for the 2026 AAOS/ABOS exams focuses on differentiating genetic orthopedic syndromes like Neurofibromatosis, Marfan, and Ehlers-Danlos. It also covers the diagnosis and management of pediatric radial fractures, emphasizing key clinical criteria and treatment principles for board success.
Comprehensive 100-Question Exam
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Question 1
Figures 39a and 39b show the radiographs of an otherwise healthy 10-year-old boy who has had thigh pain and a limp for the past 9 months. Examination reveals that the left lower extremity is 1 cm shorter, with reduced flexion, abduction, and internal rotation on the left side. The patient is at the 50th percentile for height and the 90th percentile for weight. Serum studies will most likely show

Explanation
Question 2 High Yield
An axillary nerve lesion may cause weakness in the deltoid and the
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Question 3
A young active patient with a complete isolated posterior cruciate ligament (PCL) tear undergoes a double bundle PCL reconstruction. The tensioning pattern of the anterolateral (AL) and posteromedial (PM) bundles most likely to reproduce the most normal knee kinematics would be to tension
Explanation
Question 4
A 67-year-old woman is seen in the emergency department after falling at home. Radiographs before and after treatment are shown in Figures 49a and 49b, respectively. Which of the following best explains the 8-week postinjury clinical findings seen in Figure 49c?

Explanation
Question 5
A 58-year-old woman who underwent a successful total hip replacement for degenerative arthritis 8 years ago reports groin pain for the past 6 months. A radiograph of the hip is shown in Figure 32. At revision, severe deficiency of the posterior column is noted. What reconstructive option would be most appropriate for the acetabulum?

Explanation
Question 6
Figures 50a and 50b show the standing clinical photographs of a 12-year-old boy who has had increasing pain in the left foot for the past 9 months. He reports that the pain is activity related, aching in nature, and localized to the medial aspect of the midfoot and hindfoot. History reveals that he sustained a puncture wound located superior and posterior to the medial malleolus from a plate glass window 18 months ago. Examination reveals no restriction of ankle or subtalar motion, normal neurovascular status, no masses, and a well-healed 1.5-cm laceration posterior to the superior aspect of the medial malleolus. Inversion strength of the foot is decreased to grade 3/5. Radiographs of the foot show no bony abnormalities. Treatment should consist of

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Question 7High Yield
During cemented total hip arthroplasty, peak pulmonary embolization of marrow contents occurs when the
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Question 8
The anatomy of the sciatic nerve as it exits the pelvis is best described as exiting through the

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Question 9
In a patient with a soft-tissue sarcoma treated by wide excision and radiation therapy, the risk of subsequent fracture is probably most influenced by

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Question 10High Yield
Figure 1 shows the radiograph of an 18-year-old patient who has severe knee pain. Treatment consisting of osteotomy should be perfomed

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Question 11
Which of the following orthotic features best reduces pain in patients with hallux rigidus?
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Question 12
A 78-year-old woman undergoes her third lumbar decompression and fusion from L3 to L5 without complication. On the morning of postoperative day 3, examination reveals painless, flaccid weakness of both lower extremities. She also has an absent bulbocavernous reflex and a mild saddle paresthesia. MRI scans of the lumbar spine are shown in Figures 26a and 26b. What is the most appropriate management at this time?

Explanation
Question 13
A 20-year-old man reports painless snapping about the lateral aspect of the right hip. He denies any history of trauma. Examination reveals no limp or tenderness. Hip range of motion is full, and there is good strength. Radiographs are normal. What anatomic structure is most likely causing these symptoms?
Explanation
Question 14
A 19-year-old woman reports persistent neck pain for 2 years. Pain is relieved with aspirin. A bone scan shows intense uptake in the superior, posterior portion of the C3 vertebral body. A sagittal CT reconstruction is shown in Figure 5. Treatment should consist of

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Question 15High Yield
A 21-year-old football player had severe pain and immediate swelling in the left anteromedial chest wall while bench pressing near maximal weights several days ago. Examination at the time of injury revealed a mass on the anteromedial chest wall. Follow-up examination now reveals decreased swelling, and axillary webbing is observed. The patient has weakness to adduction and forward flexion. The injured muscle originates from the
Explanation
Question 16
Figures 10a and 10b show the radiographs of a 47-year-old man who reports pain in both shoulders. He has a history of leukemia that was treated with chemotherapy and high-dose cortisone. What is the most reliable treatment option for pain relief in this patient?

Explanation
Question 17 High Yield
A 46-year-old woman reports pain and a shortened appearance of her toe after undergoing a Keller resection arthroplasty 2 years ago for hallux rigidus. Examination reveals mild swelling and motion limited to 25 degrees at the metatarsophalangeal joint. Radiographs show large dorsal osteophytes on the first metatarsal head, 50% resection of the proximal phalanx, and complete loss of the metatarsophalangeal joint space. Which of the following is considered the most reliable procedure to improve her pain and the appearance of her toe?
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Question 18
When posterior fusion with instrumentation to the sacrum is used to treat adult scoliosis, what instrumentation technique best increases the chance of a successful lumbosacral fusion?
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Question 19
A 13-year-old patient has foot drop and lateral knee pain. AP and lateral radiographs and an MRI scan are shown in Figures 49a through 49c. A biopsy specimen is shown in Figure 49d. What is the preferred method of treatment?

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Question 20
A 50-year-old woman has a painful hallux valgus and a painful callus beneath the second metatarsal head. A radiograph is shown in Figure 46. To correct these problems, treatment of the great toe deformity should consist of

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Question 21
The photomicrograph in Figure 37 shows a repaired dural tear 4 days after surgery. The material interposed between the dural edges (D) is composed of

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Question 22
A 70-year-old woman has a preoperative anterior interscalene block prior to undergoing a total shoulder arthroplasty. After seating her in the beach chair position, she becomes acutely hypotensive. What is the most likely cause for the hypotension?
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Question 23High Yield
Which of the following structures is the most important restraint to posterior subluxation of the glenohumeral joint when positioned in 90 degrees of flexion and internal rotation?

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Question 24High Yield
A 24-year-old man reports the development of a foot drop following a knee dislocation 1 year ago. The common peroneal nerve was found to be in continuity at the time of surgical reconstruction of the posterolateral corner of the knee joint. He would like to eliminate the need for an ankle-foot orthosis. What is the best option to achieve elimination of the orthosis?

Explanation
Question 25
An 18-year-old girl with quadriplegic cerebral palsy underwent posterior spinal fusion from T2 to the pelvis 3 weeks ago. She now has a low-grade fever and mild midline erythema in a 1-cm area from which there is slight clear yellowish drainage. What is the next most appropriate step in management?

Explanation
Question 26
A biopsy of the involved physis in a patient with slipped capital femoral epiphysis (SCFE) would most likely reveal
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Question 27
A 55-year-old woman with a history of untreated idiopathic scoliosis has had neurogenic claudication for the past several months. MRI reveals spinal stenosis at L2-L3, L3-L4, and L4-L5. Radiographs show a 45-degree lumbar curve from T10 to L4, with a degenerative spondylolisthesis at L4-L5. Laminectomy at the stenotic levels and stabilization of the deformity are planned. Which of the following is NOT considered an absolute indication for extending the fusion to the sacrum, rather than stopping at L5?

Explanation
Question 28
Examination of an 18-year-old professional soccer player who was forcefully kicked across the shin while attempting a slide tackle reveals a marked effusion and limited motion of the knee. The tibia translates 12 mm posterior to the femoral condyles when the knee is held in 90 degrees of flexion. There is no posteromedial or posterolateral instability. Management should consist of

Explanation
Question 29
A 17-year-old football player continues to have discomfort after sustaining a blow to his midthigh during a game 8 weeks ago. A plain radiograph is shown in Figure 13. What is the most appropriate management?

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Question 30
The spread of malignant cells to the vertebrae is often through
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Question 31
While lifting weights, a patient feels a pop in his arm. He has the deformity shown in Figure 30. If left untreated, the patient will have the greatest deficiency in

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Question 32High Yield
Which of the following best describes the course of the median nerve at the elbow?

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Question 33High Yield
Figure 1 shows the radiograph of a 60-year-old woman who underwent a previous operation for great toe pain 20 years ago. She has had increasing pain over the past 5 years and now reports pain with any motion, swelling, and clicking. She also reports pain under the ball of foot. What is the most appropriate management to alleviate her metatarsalgia and great toe pain?

Explanation
Question 34High Yield
A 13-year-old girl is referred for a painful progressive valgus deformity of the right knee. Examination reveals an antalgic gait with an obvious valgus deformity. The right distal femur has a palpable, tender mass with erythema and warmth. Figures 4a and 4b show a clinical photograph and a radiograph. Management should consist of

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Question 35High Yield
What is the most common complication associated with scalene regional anesthesia for shoulder procedures?
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Question 36 High Yield
A 10-year-old girl has a midshaft both bone forearm fracture. After attempted closed reduction, alignment consists of bayonet apposition, 10 degrees of malrotation, and 8 degrees of volar angulation. Management should now consist of

Detailed Explanation
Question 37High Yield
Which of the following is associated with the use of bisphosphonates in the setting of metastatic breast cancer to the spine?
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Question 38 High Yield
Titanium and its alloys are unsuitable candidates for which of the following implant applications?

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Question 39High Yield
A 42-year-old woman with a long-standing history of rheumatoid arthritis undergoes total shoulder arthroplasty for persistent pain that has failed to respond to nonsurgical management. Intraoperative radiographs reveal an oblique, minimally displaced fracture of the greater tuberosity. Based on these findings, what is the best course of action?

Explanation
Question 40High Yield
A 52-year-old man who was a former high school pitcher now reports loss of elbow flexion and extension with pain at the extremes of motion. Nonsurgical management has failed to provide relief. Examination reveals movement from 50 degrees to 110 degrees and is painful only at the limits of motion. A radiograph is shown in Figure 12. Treatment should consist of

Explanation
Question 41
Pain associated with a proximal medial tibial osteochondroma in a 10-year-old patient is most commonly the result of
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Question 42High Yield
A patient with diabetic peripheral neuropathy undergoes a partial first ray amputation for a chronic ulcer beneath the first metatarsal head. The insertion of the anterior tibialis is preserved. The patient has 10 degrees of passive dorsiflexion at the ankle and no other foot deformities or ulcers. Which of the following is considered appropriate shoe wear for this patient?
Explanation
Question 43
A 25-year-old woman who fell on her outstretched hand reports chronic pain over the hypothenar eminence region and some dorsal ulnar wrist pain. She also notes difficulty playing golf and tennis. Plain radiographs of the hand and wrist are unremarkable. A CT scan is shown in Figure 36. What is the next most appropriate step in management?

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Question 44
Which of the following is considered a potential advantage in prophylaxis for the prevention of deep venous thrombosis associated with the use of low-molecular weight heparin (LMWH) as compared with fixed-dose unfractionated heparin?

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Question 45
What is the most common adverse postoperative complication of laminoplasty for multilevel cervical spondylotic myelopathy?

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Question 46
A 65-year-old man has a painful right hip mass that has been growing for several years. A radiograph, CT scan, and photomicrograph are shown in Figures 56a through 56c. What is the most appropriate treatment?

Explanation
Question 47 High Yield
A 20-year-old football player has repeated episodes of heat cramps during summer training sessions. A deficiency of what electrolyte is most responsible for heat cramps?
Detailed Explanation
Question 48
A 42-year-old woman has a history of nontraumatic ankle swelling with tenderness over the Achilles tendon and plantar fascia. She reports that while vacationing in Connecticut 2 months ago she noted the presence of a "red bull's eye" rash. Management should consist of
Explanation
Question 49
Figure 11 shows a consecutive sequence of MRI scans obtained in a 12-year-old boy who has had increasing lateral knee pain and catching for the past 6 months. Examination reveals pain localized to the lateral joint line. Range-of-motion testing reveals a 5-degree lack of full extension on the involved side. Plain radiographs and laboratory values are within normal limits. What is the most appropriate management?

Explanation
Question 50
Patients with patellar clunk syndrome are best managed by which of the following methods?

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Question 51
A 62-year-old patient with rheumatoid arthritis has had pain and instability of the elbow following total elbow replacement 2 years ago. A complete work-up, including aspiration and cultures, is negative. Figures 9a and 9b show the AP and lateral radiographs. Treatment should consist of

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Question 52 High Yield
An otherwise healthy 54-year-old man who underwent a successful multilevel lumbar decompression and fusion 4 years ago now reports increasingly severe bilateral thigh claudication with paresthesia and severe back pain for the past 12 months. Physical therapy, bracing, and epidural steroids have failed to provide relief. A radiograph and MRI scans are shown in Figures 15a through 15c. He is afebrile, and laboratory studies show an erythrocyte sedimentation rate of 5 mm/h and a normal WBC count. What is the best course of action?

Detailed Explanation
Question 53
A 2-year-old girl has had a 2-day history of fever and refuses to move her left shoulder following varicella. Laboratory studies show an erythrocyte sedimentation rate of 75 mm/h and a peripheral WBC count of 18,000/mm3. What is the most common organism in this scenario?

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Question 54High Yield
A 24-year-old woman has a spleen laceration and hypotension. Radiographs reveal a pulmonary contusion and a displaced mid-diaphyseal fracture of the femur. The trauma surgeon clears her for stabilization of the femoral fracture. What technique will offer the least potential for initial complications?

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Question 55 High Yield
Which of the following best describes heat stroke?
Detailed Explanation
Question 56High Yield
What radiographic view will best reveal degeneration of the pisotriquetral joint in a patient who is being evaluated for pisotriquetral arthrosis?
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Question 57High Yield
What neurovascular structure is most at risk when performing an inside-out repair of the posterior horn of the medial meniscus?
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Question 58
A 25-year-old man sustained a head injury after being ejected from his car. Examination reveals a Glasgow Coma Scale score of 7 and a swollen right knee. Clinical examination shows that the knee is very unstable, suggesting tears of the medial collateral and anterior and posterior cruciate ligaments, as well as the posterior lateral corner. What is the most appropriate first step to rule out a vascular injury?
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Question 59High Yield
Which of the following is a recognized consequence of hip fusion?

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Question 60High Yield
A corset-type brace may help reduce symptoms during an episode of acute low back pain as the result of
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Question 61 High Yield
A cord-like middle glenohumeral ligament and absent anterosuperior labrum complex can be a normal anatomic capsulolabral variant. If this normal variation is repaired during arthroscopy, it will cause

Detailed Explanation
Question 62
When performing an arthroscopic subacromial decompression, bleeding can be encountered when dividing the coracoacromial ligament because of injury to what artery?
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Question 63 High Yield
When using surgery extending to the pelvis to treat long spinal deformity in adults, the addition of anterior interbody structural support at the lumbosacral junction serves what biomechanical function?
Detailed Explanation
Question 64High Yield
A 45-year-old man is seeking evaluation of an injury sustained in a motor vehicle accident 10 weeks ago. Current radiographs are shown in Figures 2a and 2b. Based on the radiographic findings, what is the most likely diagnosis?

Explanation
Question 65
A 60-year-old woman has a mass in the right scapula. Figures 25a and 25b show a CT scan and a biopsy specimen. The cells are lymphocyte common antigen positive, Ewing's specific antigen (CD99) negative, and keratin negative. What is the next step in management?

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Question 66
Figure 30 shows an axial cross section of extensor tendon anatomy in zone 7 of the wrist. What letter best depicts the location of the posterior interosseous nerve?

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Question 67High Yield
What is the most common complication following interscalene nerve block for shoulder surgery?
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Question 68 High Yield
A 22-year-old college basketball player who was hit from behind while going up for a rebound is rendered immediately quadraparetic for approximately 10 minutes, followed by complete resolution of motor loss and return of full sensation. The radiograph and MRI scan of the cervical spine shown in Figures 2a and 2b reveal a canal diameter of 13 mm, loss of cerebrospinal fluid space about the spinal cord, and no signal change within the cord. What is the best course of action?

Detailed Explanation
Question 69
A 54-year-old man sustained a small superficial abrasion over the left acromioclavicular joint after falling from his bicycle. Examination reveals no other physical findings. Radiographs show a displaced fracture of the lateral end of the clavicle distal to a line drawn vertically to the coracoid process. Management should consist of

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Question 70
When performing the exposure for an anterior approach to the cervical spine, the surgical dissection should not enter the plane between the trachea and the esophagus and excessive retraction should be avoided to prevent injury to the
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Question 71
Figures 8a through 8c show the lateral radiograph and T1- and T2-weighted MRI scans of a 14-year-old soccer player who reports aching thigh pain. The next most appropriate step in management should consist of

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Question 72
An 82-year-old woman reports right buttock pain after a car trip. Laboratory studies show an erythrocyte sedimentation rate of 30 mm/h and WBC of 4,600/mm3. Figure 34a shows a plain AP radiograph of the pelvis, and Figure 34b shows a delayed technetium Tc 99m bone scan. Management should consist of

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Question 73 High Yield
Which of the following is considered a reasonable goal for arthroplasty surgery in rotator cuff arthropathy?
Detailed Explanation
Question 74High Yield
A 32-year-old man has an open comminuted humeral shaft fracture. Examination reveals absence of sensation in the first web space and he is unable to fully extend the thumb, fingers, and wrist. What is the recommended treatment following irrigation and debridement of the fracture?

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Question 75
Figures 49a and 49b show MRI scans of the shoulder. What is the most likely diagnosis?

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Question 76
A 43-year-old former professional hockey player reports severe pain in his chest after being checked from the side in a pick-up hockey game. An MRI scan and plain radiographs are shown in Figures 25a through 25c. What is the most likely diagnosis?

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Question 77High Yield
A 35-year-old woman with type 1 diabetes mellitus has been treated for the past 2 years at a wound care center for persistent bilateral fifth metatarsal head ulcers. Management has consisted of shoe wear modifications, treatment with multiple enzymatic ointments, and a fifth metatarsal head resection on the left side. Physical examination reveals intact pulses, minimal ankle dorsiflexion, neutral hindfoot, and a persistent ulcer under the fifth metatarsal heads. What treatment will best help heal the ulcers?
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Question 78
The nerve to the abductor digiti quinti, implicated in some patients who have chronic heel pain, is most commonly a branch of what larger nerve?
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Question 79
A 30-year-old woman injures her knee while skiing. Based on the MRI scan shown in Figure 5, treatment should consist of

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Question 80High Yield
Figures 27a and 27b show the radiographs of a 32-year-old woman who was involved in a high-speed motor vehicle accident. She is neurologically intact. After stabilization and assessment, treatment should consist of

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Question 81
A 58-year-old man reports a 2-month onset of groin pain with no history of trauma. Examination reveals that range of motion of the hip is mildly restricted, and he has pain with both weight bearing and at rest. An MRI scan is shown in Figure 20. Treatment should consist of

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Question 82 High Yield
The radiograph shown in Figure 27 shows measurement of what angle?

Detailed Explanation
Question 83
A 52-year-old man has had right shoulder pain in the deltoid region that increases at night for the past 2 months. He denies any history of trauma. Examination reveals mild tenderness over the greater tuberosity, and the Neer and Hawkins impingement signs are positive. AP and outlet lateral radiographs are shown in Figures 24a and 24b. Initial management should consist of

Explanation
Question 84
A 28-year-old man reports knee stiffness, swelling, and a constant ache that is worse with activity. Examination reveals an effusion, global tenderness, and warmth to the touch. Flexion is limited to 110 degrees. Figures 48a through 48d show sagittal T1-weighted, sagittal T2-weighted, axial T1-weighted fat-saturated gadolinium, and axial gradient echo MRI scans. Based on these findings, what is the most likely diagnosis?

Explanation
Question 85High Yield
During the evaluation of a patient suspected of having a lumbar disk herniation, T1- and T2-weighted MRI scans reveal a hyperintence lobular, well-defined lesion in the L2 vertebral body. What is the most likely diagnosis?

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Question 86
Which of the following factors is most commonly associated with mechanical failure of a cemented total hip arthroplasty?

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Question 87
Pacinian corpuscles are lamellated nerve endings that are responsible for providing the perception of

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Question 88High Yield
An 83-year-old woman with a long history of her foot slowly and progressively "turning out" now reports significant ankle pain. History reveals that she has significant cardiac disease and exercise-induced angina. Examination reveals a deficiency in the posterior tibial tendon; however, the hindfoot remains moderately supple. Radiographs reveal a valgus tilt of the tibiotalar joint and early arthrosis. What is the most appropriate orthotic management?
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Question 89
Based on the findings seen in the posteroanterior radiograph of the wrist shown in Figure 17, which of the following structures is torn?

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Question 90 High Yield
A 66-year-old man reports a 2-week history of worsening low back and leg pain. He reports that his pain is aggravated by lying down and relieved by standing and walking. He notes that he has been losing weight recently and that his pain has been awakening him during the night. His medical history is significant for hypertension, coronary artery disease, and prostate cancer. His physical examination is essentially unremarkable. Lumbar radiographs are within normal limits. What is the most appropriate management for this patient?
Detailed Explanation
Question 91
Which of the following muscles has dual innervation?

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Question 92 High Yield
A 75-year-old woman began a walking program 2 months after undergoing right total knee arthroplasty. She had to stop the program after 4 weeks because of hindfoot pain and ankle swelling. Radiographs are shown in Figures 42a and 42b. What is the most likely diagnosis?

Detailed Explanation
Question 93
In the treatment of all magnitudes of bunionette deformities, what is the most common complication associated with lateral condylectomy of the fifth metatarsal head?
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Question 94High Yield
A patient undergoes hip arthroscopy, and the pathology is seen in Figure 18. What is the most likely diagnosis?

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Question 95 High Yield
With a full-thickness articular cartilage injury, the body's healing response produces cartilage mainly composed of what type of collagen?
Detailed Explanation
Question 96
A 20-year-old man sustained a closed tibial fracture and is treated with a reamed intramedullary nail. What is the most common complication associated with this treatment?

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Question 97
A posterolateral approach to the tibial plafond proceeds between what two muscles?

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Question 98
A 62-year-old man who underwent total knee arthroplasty 6 months ago now reports pain after falling on the anterior portion of the knee. Examination reveals weakness of knee extension but no extensor lag. Flexion that had once measured 115 degrees is now limited to 70 degrees because of pain. A radiograph is shown in Figure 25. Management should now consist of

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Question 99
In the preoperative planning of revision acetabular reconstruction, the surgeon should identify significant posterior column deficiency by noting which of the following radiographic features?
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Question 100High Yield
A 17-year-old high school football player reports wrist pain after being tackled. Radiographs are shown in Figures 22a through 22c. What is the recommended intervention?

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