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Orthopaedic oncology Generic structured oral examination question 3: Staging

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Orthopaedic oncology Generic structured oral examination question 3: Staging

EXAMINER: So what stage is this tumour?

 

CANDIDATE: I would stage this tumour using the Musculoskeletal Tumour Society staging system as described

 

Table 7.1 Enneking/MSTS staging system.2

 

Stage

Description

Grade

Site

Metastases

IA

Low-grade, intracompartmental

G1

T1

M0

IB

Low-grade, extracompartmental

G1

T2

M0

IIA

High-grade, intracompartmental

G2

T1

M0

IIB

High-grade, extracompartmental

G2

T2

M0

III

Any grade, metastatic

G1–2

T1–2

M1

 

 

by Enneking.1 We have discussed that it is a high-grade osteosarcoma, which makes it at least Stage II. Its an intramedullary tumour that has invaded the surrounding soft- tissues making it extracompartmental, and upstaging it to IIB. Weve not discussed whether there is any evidence of metastasis yet, but, if there is, that would immediately make it a Stage III, regardless of the other features weve talked about.

General advice: This question will usually follow a discussion about a malignant tumour, for example osteosarcoma as in this example. The Enneking system (Table 7.1) is the easiest to remember and can be applied equally to bony and soft-tissue sarco- mas.2 The other commonly used system is the Ameri- can Joint Committee on Cancer (AJCC) system, which is more complicated. The AJCC also have separate systems for bony and soft-tissue tumours.

 

  1. Enneking WF, Spanier SS, Goodman MA. Current concepts review. The surgical staging of musculoskeletal sarcoma. J Bone Joint Surg Am 1980;62-A:10271030.

  2. NCCN. National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Soft Tissue Sarcoma. V.2.2008. National Comprehensive Cancer Network, 2008.

 

Orthopaedic

Orthopaedic oncology Generic structured oral examination question 3: Staging

EXAMINER: So what stage is this tumour?

 

CANDIDATE: I would stage this tumour using the Musculoskeletal Tumour Society staging system as described

 

Table 7.1 Enneking/MSTS staging system.2

 

Stage

Description

Grade

Site

Metastases

IA

Low-grade, intracompartmental

G1

T1

M0

IB

Low-grade, extracompartmental

G1

T2

M0

IIA

High-grade, intracompartmental

G2

T1

M0

IIB

High-grade, extracompartmental

G2

T2

M0

III

Any grade, metastatic

G1–2

T1–2

M1

 

 

by Enneking.1 We have discussed that it is a high-grade osteosarcoma, which makes it at least Stage II. Its an intramedullary tumour that has invaded the surrounding soft- tissues making it extracompartmental, and upstaging it to IIB. Weve not discussed whether there is any evidence of metastasis yet, but, if there is, that would immediately make it a Stage III, regardless of the other features weve talked about.

General advice: This question will usually follow a discussion about a malignant tumour, for example osteosarcoma as in this example. The Enneking system (Table 7.1) is the easiest to remember and can be applied equally to bony and soft-tissue sarco- mas.2 The other commonly used system is the Ameri- can Joint Committee on Cancer (AJCC) system, which is more complicated. The AJCC also have separate systems for bony and soft-tissue tumours.

 

  1. Enneking WF, Spanier SS, Goodman MA. Current concepts review. The surgical staging of musculoskeletal sarcoma. J Bone Joint Surg Am 1980;62-A:10271030.

  2. NCCN. National Comprehensive Cancer Network Clinical Practice Guidelines in Oncology: Soft Tissue Sarcoma. V.2.2008. National Comprehensive Cancer Network, 2008.

 

 

Dr. Mohammed Hutaif

About the Author: Prof. Dr. Mohammed Hutaif

Vice Dean of the Faculty of Medicine at Sana'a University and a leading consultant in orthopedic and spinal surgery. Learn more about my expertise and achievements.

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