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Question 5161

Topic: 7. Hand and Wrist

The transverse carpal ligament forms the volar roof of the carpal tunnel. Which of the following pairs of carpal bones serve as the radial attachments for this structure?

. Scaphoid and trapezium
. Scaphoid and trapezoid
. Trapezium and hook of the hamate
. Pisiform and hook of the hamate
. Triquetrum and pisiform

Correct Answer & Explanation

. Scaphoid and trapezium


Explanation

Correct Answer: AThe transverse carpal ligament attaches radially to the scaphoid tuberosity and the crest of the trapezium. Ulnarly, it attaches to the pisiform and the hook of the hamate. The trapezoid and ulna do not serve as attachment points for the transverse carpal ligament.

Question 5162

Topic: Wrist & Carpus

A 45-year-old woman undergoes volar locked plating for a distal radius fracture

. At 6 months post-op, she suddenly loses the ability to actively flex her thumb interphalangeal joint. What surgical technical error most likely caused this complication?

. Dorsal screw penetration past the extensor cortex
. Plate placement distal to the watershed line
. Over-tightening of the brachioradialis insertion
. Failure to repair the pronator quadratus
. Placement of the plate deep to the flexor carpi radialis sheath

Correct Answer & Explanation

. Plate placement distal to the watershed line


Explanation

Attritional rupture of the flexor pollicis longus (FPL) tendon is a known complication of volar plating for distal radius fractures. It is most commonly caused by placing the plate too far distally, protruding anterior to the watershed line and impinging on the flexor tendons.

Question 5163

Topic: 7. Hand and Wrist

A 55-year-old woman with end-stage renal disease on hemodialysis presents with severe bone pain. Radiographs of her hands show subperiosteal resorption on the radial aspect of her middle phalanges. What is the primary driver of these osseous changes?

. Decreased parathyroid hormone levels
. Excessive aluminum deposition in the bone
. Decreased production of 1,25-dihydroxyvitamin D by the kidneys
. Autonomous overproduction of calcitonin
. Monoclonal gammopathy of undetermined significance

Correct Answer & Explanation

. Decreased production of 1,25-dihydroxyvitamin D by the kidneys


Explanation

Renal osteodystrophy features secondary hyperparathyroidism. Failing kidneys cannot adequately convert 25-hydroxyvitamin D to active 1,25-dihydroxyvitamin D, leading to hypocalcemia and a compensatory, destructive rise in PTH.

Question 5164

Topic: 7. Hand and Wrist

A 4-year-old girl with Hurler syndrome presents with bilateral stiffness and contractures of her fingers. On examination, she has multiple trigger digits. What is the primary pathophysiologic cause of the trigger digits in this patient population?

. A1 pulley hypertrophy
. Accumulation of glycosaminoglycans within the flexor tendon and synovium
. Congenital absence of the flexor digitorum superficialis
. Carpal tunnel syndrome
. Ischemic contracture of the intrinsic muscles

Correct Answer & Explanation

. Accumulation of glycosaminoglycans within the flexor tendon and synovium


Explanation

Trigger digits in patients with mucopolysaccharidoses (like Hurler syndrome) are caused by the direct infiltration and accumulation of glycosaminoglycans within the flexor tendons and tenosynovium, causing an intrinsic size mismatch with the pulley system.

Question 5165

Topic: 7. Hand and Wrist

A 3-year-old child presents with coarse facies, corneal clouding, and a thoracolumbar kyphosis. Radiographs of the hands demonstrate proximal pointing of the metacarpals.

Which enzyme is most likely deficient in this patient?

. Galactose-6-sulfatase
. Iduronate-2-sulfatase
. Alpha-L-iduronidase
. Beta-glucuronidase
. Sphingomyelinase

Correct Answer & Explanation

. Alpha-L-iduronidase


Explanation

The clinical features and 'bullet-shaped' (proximally pointed) metacarpals are classic for Hurler syndrome (MPS I). This disorder is caused by a deficiency in the enzyme alpha-L-iduronidase.

Question 5166

Topic: Nerve & Tendon

A 40-year-old female undergoes a mini-open carpal tunnel release. Post-operatively, she complains of an inability to palmar abduct her thumb. Examination shows weakness of the abductor pollicis brevis, but normal sensation in the radial 3.5 digits. Which structure was most likely injured?

. Ulnar nerve
. Recurrent motor branch of the median nerve
. Superficial branch of the radial nerve
. Anterior interosseous nerve
. Deep branch of the ulnar nerve

Correct Answer & Explanation

. Recurrent motor branch of the median nerve


Explanation

The recurrent motor branch of the median nerve innervates the abductor pollicis brevis, opponens pollicis, and the superficial head of the flexor pollicis brevis. Its injury results in loss of thumb palmar abduction without sensory deficits.

Question 5167

Topic: 7. Hand and Wrist

A 28-year-old chef sustains a knife wound to the volar proximal phalanx of his index finger (Zone II), lacerating both the FDP and FDS tendons. A primary repair is performed. Which postoperative rehabilitation protocol yields the best outcomes regarding tendon glide and strength?

. Strict immobilization in a cast for 6 weeks
. Early passive flexion and passive extension only
. Early active range of motion utilizing a dorsal block splint
. Continuous passive motion without active engagement
. Immediate unprotected full active range of motion

Correct Answer & Explanation

. Early active range of motion utilizing a dorsal block splint


Explanation

Early active range of motion (such as the modified Belfast protocol) using a dorsal block splint has been shown to reduce tendon adhesions, improve glide, and increase ultimate tensile strength compared to strict immobilization or passive-only protocols.

Question 5168

Topic: 7. Hand and Wrist

A 55-year-old woman presents with severe bilateral nighttime hand numbness and thenar atrophy. Electromyography confirms severe median neuropathy at the wrist. During an open carpal tunnel release, which specific structure is sectioned to decompress the nerve?

. Volar carpal ligament
. Transverse carpal ligament
. Palmar aponeurosis
. Flexor retinaculum only
. Extensor retinaculum

Correct Answer & Explanation

. Transverse carpal ligament


Explanation

The transverse carpal ligament forms the roof of the carpal tunnel. Sectioning this specific ligament is the critical step in carpal tunnel release to relieve pressure on the median nerve.

Question 5169

Topic: Wrist & Carpus

A 60-year-old woman is treated for a dorsally angulated distal radius fracture with a volar locking plate. Six weeks postoperatively, she suddenly loses the ability to actively extend her thumb interphalangeal joint. What is the most likely cause of this complication?

. Irritation and attritional rupture from dorsally prominent screws
. Irritation from a prominent volar plate at the watershed line
. Spontaneous attritional rupture over Lister's tubercle
. Avascular necrosis of the extensor pollicis longus tendon
. Missed iatrogenic laceration during the initial surgical exposure

Correct Answer & Explanation

. Irritation and attritional rupture from dorsally prominent screws


Explanation

Extensor pollicis longus (EPL) tendon rupture following volar plating of the distal radius is most commonly caused by iatrogenic dorsal screw prominence. The screws penetrate the dorsal cortex and cause attritional wear on the overlying extensor tendons.

Question 5170

Topic: 7. Hand and Wrist

A patient with Ellis-van Creveld (chondroectodermal dysplasia) syndrome presents for orthopedic evaluation of postaxial polydactyly and genu valgum. Which of the following systemic manifestations is most commonly associated with this syndrome and requires preoperative medical clearance?

. Tetralogy of Fallot
. Atrial septal defect
. Ventricular septal defect
. Coarctation of the aorta
. Patent ductus arteriosus

Correct Answer & Explanation

. Atrial septal defect


Explanation

Chondroectodermal dysplasia (Ellis-van Creveld syndrome) is strongly associated with congenital heart defects, seen in up to 60% of cases. The most common cardiac anomaly is an atrial septal defect (ASD) or a single atrium.

Question 5171

Topic: 7. Hand and Wrist

A 5-year-old Amish child presents with disproportionate short stature, postaxial polydactyly of the hands, and a history of an atrial septal defect repair. Radiographs show hypoplastic distal phalanges. What is the most likely diagnosis?

. Achondroplasia
. Chondroectodermal dysplasia (Ellis-van Creveld syndrome)
. Asphyxiating thoracic dystrophy (Jeune syndrome)
. Diastrophic dysplasia
. Cleidocranial dysplasia

Correct Answer & Explanation

. Chondroectodermal dysplasia (Ellis-van Creveld syndrome)


Explanation

Chondroectodermal dysplasia (Ellis-van Creveld syndrome) is an autosomal recessive disorder common in the Amish population. It is characterized by short-limbed dwarfism, postaxial polydactyly, and congenital heart defects (mostly ASDs).

Question 5172

Topic: Wrist & Carpus

A 45-year-old female is 8 weeks status post closed reduction and cast immobilization for a distal radius fracture. She complains of severe, burning pain that is disproportionate to the injury, along with skin color changes and stiffness.

Radiographs show patchy osteopenia. Which intervention has been shown to reduce the incidence of this condition when administered daily following a distal radius fracture?

. Calcium and Vitamin D
. Vitamin C (500 mg daily for 50 days)
. Gabapentin (300 mg TID)
. Prednisone taper over 2 weeks
. Prophylactic stellate ganglion block

Correct Answer & Explanation

. Vitamin C (500 mg daily for 50 days)


Explanation

This patient has Complex Regional Pain Syndrome (CRPS) or Sudeck's atrophy. Daily administration of 500 mg of Vitamin C for 50 days after a distal radius fracture has been shown to significantly decrease the risk of developing CRPS.

Question 5173

Topic: 7. Hand and Wrist

A 55-year-old female presents 8 weeks after closed reduction and casting of a distal radius fracture. She reports intense, burning pain, swelling, and vasomotor changes in her hand. Radiographs show patchy periarticular osteopenia.

Which of the following prophylactic measures has been prospectively shown to reduce the incidence of this condition when administered at the time of injury?

. Oral bisphosphonates
. Vitamin C 500 mg daily
. Gabapentin 300 mg daily
. Early open reduction and internal fixation
. Systemic corticosteroid dose pack

Correct Answer & Explanation

. Vitamin C 500 mg daily


Explanation

This patient has developed Complex Regional Pain Syndrome (CRPS), historically known as Sudeck's atrophy. Prophylactic administration of Vitamin C at a dose of 500 mg daily for 50 days following a distal radius fracture has been shown to significantly reduce the risk of developing CRPS. It is believed to work via its antioxidant properties.

Question 5174

Topic: Wrist & Carpus

A 45-year-old female is treated conservatively for a distal radius fracture. Eight weeks later, she develops severe burning pain out of proportion to the injury, along with skin changes and stiffness. Radiographs show patchy, periarticular osteopenia.

What is the best pharmacologic prophylaxis that could have been prescribed at the time of injury to reduce her risk of developing this condition?

. Gabapentin
. Vitamin C
. Prednisone
. Amitriptyline
. Ibuprofen

Correct Answer & Explanation

. Vitamin C


Explanation

The patient has Complex Regional Pain Syndrome (CRPS) Type I. Vitamin C (500mg daily for 50 days) has been shown in some studies to reduce the incidence of CRPS following distal radius fractures.

Question 5175

Topic: Nerve & Tendon

A 35-year-old male develops chronic, severe burning pain and allodynia in his forearm following a recognized median nerve injury from a glass laceration. What feature distinguishes his diagnosis of CRPS Type II from CRPS Type I?

. Presence of patchy, periarticular osteopenia
. Presence of a definable peripheral nerve injury
. Favorable response to sympathetic ganglion blocks
. Involvement limited strictly to the upper extremity
. Presence of trophic skin and nail changes

Correct Answer & Explanation

. Presence of a definable peripheral nerve injury


Explanation

CRPS is divided into Type I (formerly Reflex Sympathetic Dystrophy) and Type II (formerly Causalgia). The defining difference is that Type II involves a verified, definable peripheral nerve injury.

Question 5176

Topic: 7. Hand and Wrist

A 40-year-old woman develops CRPS Type I of the hand and wrist.

She is completely intolerant of physical therapy due to extreme allodynia, and she has failed NSAIDs, gabapentin, and oral steroids. Which intervention is most appropriate next to facilitate active range of motion therapy?

. Below elbow amputation
. Stellate ganglion block
. Lumbar sympathetic block
. Prophylactic carpal tunnel release
. Intravenous pamidronate

Correct Answer & Explanation

. Stellate ganglion block


Explanation

When oral medications fail to control symptoms enough to allow physical therapy in upper extremity CRPS, a sympathetic block (Stellate ganglion block) is indicated to provide temporary pain relief and facilitate functional rehabilitation.

Question 5177

Topic: Wrist & Carpus



A 45-year-old female presents 8 weeks after ORIF of a distal radius fracture with severe burning pain, swelling, and shiny skin. Radiographs show patchy osteopenia. Which prophylactic medication given post-operatively could have significantly reduced her risk of developing this condition?

. Calcium supplementation
. Vitamin C (Ascorbic acid)
. Oral bisphosphonates
. Non-steroidal anti-inflammatory drugs
. Pregabalin

Correct Answer & Explanation

. Vitamin C (Ascorbic acid)


Explanation

The patient has Complex Regional Pain Syndrome (CRPS), also known as Sudeck's atrophy. Prophylactic administration of Vitamin C (500 mg daily for 50 days) after a distal radius fracture has been shown to decrease the incidence of CRPS.

Question 5178

Topic: Wrist & Carpus

A 55-year-old female sustains a distal radius fracture. To prevent the complication shown in the radiograph

, what pharmacological prophylaxis has historically been recommended during the conservative management of this injury?

. Gabapentin 300mg daily
. Vitamin C 500mg daily
. Ibuprofen 600mg every 8 hours
. Prednisone 10mg daily
. Amitriptyline 25mg nightly

Correct Answer & Explanation

. Vitamin C 500mg daily


Explanation

Vitamin C (500 mg daily for 50 days) has been shown in some studies to reduce the incidence of Complex Regional Pain Syndrome (CRPS) following distal radius fractures. CRPS is characterized by pain out of proportion, sudomotor changes, and patchy osteopenia.

Question 5179

Topic: 7. Hand and Wrist

A 48-year-old female presents 12 weeks after a closed reduction of a distal radius fracture complaining of severe, burning hand pain. Examination reveals glossy, erythematous skin, profound stiffness, and hypersensitivity.

Which of the following criteria is the internationally accepted standard for diagnosing this condition?

. Jones criteria
. Budapest criteria
. SINS criteria
. Mirels criteria
. Kocher criteria

Correct Answer & Explanation

. Budapest criteria


Explanation

The Budapest criteria are the standardized clinical diagnostic criteria for Complex Regional Pain Syndrome (CRPS). They require the presence of disproportionate pain along with specific sensory, vasomotor, sudomotor/edema, and motor/trophic findings.

Question 5180

Topic: 7. Hand and Wrist

A 50-year-old female presents 3 months after a conservatively treated distal radius fracture with a stiff, swollen, erythematous hand, and severe allodynia. Radiographs show periarticular osteopenia.

What is the primary autonomic nervous system dysfunction mediating her symptoms?

. Parasympathetic hyperactivity
. Sympathetic hyperactivity
. Somatic nerve demyelination
. Acetylcholine receptor blockade
. Loss of dorsal root ganglion function

Correct Answer & Explanation

. Sympathetic hyperactivity


Explanation

Complex Regional Pain Syndrome (CRPS) is driven by abnormal sympathetic nervous system hyperactivity. This leads to vasomotor and sudomotor changes, severe allodynia, and trophic skin changes.