This practice set contains high-yield board review questions covering key concepts in 6. Spine. Each clinical scenario is designed to test your diagnostic and management skills relevant to this subspecialty.
Question 7041
Topic: 6. Spine
A 45-year-old male with severe ankylosing spondylitis presents with a fixed thoracolumbar kyphosis. A pedicle subtraction osteotomy (PSO) is planned. Which anatomical level is typically the safest and most appropriate for a PSO to correct global sagittal imbalance?
Correct Answer & Explanation
. L3
Explanation
An L3 pedicle subtraction osteotomy is typically preferred for correcting severe sagittal imbalance in ankylosing spondylitis. L3 is safely below the conus medullaris and is close to the normal apex of lumbar lordosis.
Question 7042
Topic: 6. Spine
A 14-year-old non-ambulatory male with Duchenne Muscular Dystrophy (DMD) has a progressive 45-degree scoliosis. His FVC is currently 40% of predicted. What is the most appropriate management?
Correct Answer & Explanation
. Posterior spinal fusion from the upper thoracic spine to the pelvis
Explanation
In DMD, progressive scoliosis is almost inevitable and bracing is ineffective. Posterior spinal fusion to the pelvis is indicated when curves exceed 20-30 degrees and should be done before FVC severely declines (typically <30%).
Question 7043
Topic: 6. Spine
A 24-year-old male presents with chronic insidious-onset lower back pain that improves with exercise but not with rest. Which initial radiographic finding is most characteristic of early Ankylosing Spondylitis?
Correct Answer & Explanation
. Bilateral sacroiliac joint widening with subchondral sclerosis
Explanation
The earliest radiographic changes in Ankylosing Spondylitis occur in the sacroiliac joints, characterized by symmetric widening, blurring, and subchondral sclerosis (sacroiliitis). Vertebral squaring and "bamboo spine" are late findings.
Question 7044
Topic: 6. Spine
A 3-year-old child presents with a progressive 60-degree idiopathic scoliosis. What is the primary rationale for utilizing a growth-friendly construct rather than an immediate definitive spinal fusion?
Correct Answer & Explanation
. To prevent thoracic insufficiency syndrome and allow alveolar development
Explanation
Early spinal fusion in young children arrests thoracic growth, leading to restricted lung volumes and thoracic insufficiency syndrome. Growth-friendly constructs allow continued spine and thoracic growth, facilitating crucial alveolar development.
Question 7045
Topic: 6. Spine
A 55-year-old male with long-standing ankylosing spondylitis sustains a low-energy fall. CT imaging reveals an acute extension-distraction fracture through the T10-T11 ossified disc space. Due to the altered biomechanics of the ankylosed spine, this patient is at the highest risk for which of the following acute complications?
Correct Answer & Explanation
. Epidural hematoma
Explanation
The ankylosed spine fractures like a long tubular bone ("chalk-stick" fracture), often resulting in highly unstable shear or extension-distraction injuries. There is a high risk of epidural hematoma and neurologic deterioration due to tearing of the epidural venous plexus and continuous bleeding from the cancellous bone.
Question 7046
Topic: 6. Spine
Achondroplasia is the most common form of short-limb dwarfism and frequently presents with spinal manifestations. Which of the following radiographic findings is a hallmark of the lumbar spine in patients with this condition?
Correct Answer & Explanation
. Decreased interpedicular distance from L1 to L5
Explanation
In normal individuals, the interpedicular distance increases from L1 to L5. In achondroplasia, short and thickened pedicles result in a pathognomonic progressive decrease in interpedicular distance from L1 to L5, strongly predisposing the patient to symptomatic spinal stenosis.
Question 7047
Topic: 6. Spine
In the evaluation of a 6-month-old infant with infantile idiopathic scoliosis, which of the following radiographic parameters is most highly predictive of curve progression?
Correct Answer & Explanation
. Rib-vertebra angle difference (RVAD) greater than 20 degrees
Explanation
Mehta's rib-vertebra angle difference (RVAD) is critical in evaluating infantile idiopathic scoliosis. An RVAD greater than 20 degrees (Phase II) strongly correlates with a high likelihood of progressive deformity, whereas curves with an RVAD less than 20 degrees often resolve spontaneously.
Question 7048
Topic: 6. Spine
A 45-year-old male with severe ankylosing spondylitis presents with a fixed "chin-on-chest" deformity, rendering him unable to gaze horizontally. Surgical correction is planned. Which anatomic level is generally preferred for an extension osteotomy to correct this specific deformity?
Correct Answer & Explanation
. C7-T1
Explanation
The cervicothoracic junction (C7-T1) is the preferred site for a corrective extension osteotomy in ankylosing spondylitis. The spinal canal is relatively wide at this level, and the osteotomy is performed below the cervical enlargement, reducing the risk of devastating spinal cord injury.
Question 7049
Topic: 6. Spine
A 13-year-old boy with Duchenne Muscular Dystrophy (DMD) has recently become wheelchair-bound. His forced vital capacity (FVC) is 50% of predicted, and standing radiographs reveal a progressive 35-degree thoracolumbar scoliosis with significant pelvic obliquity. What is the most appropriate management?
Correct Answer & Explanation
. Posterior spinal fusion from the upper thoracic spine to the pelvis
Explanation
In DMD, once a patient is wheelchair-bound and develops a curve over 20-30 degrees, prompt posterior spinal fusion to the pelvis is indicated. Delaying surgery leads to further decline in pulmonary function, dramatically increasing perioperative morbidity, and bracing is ineffective for these paralytic curves.
Question 7050
Topic: 6. Spine
In predicting the natural history of congenital scoliosis, the morphological type of the vertebral anomaly is the most critical factor. Which of the following anomalies carries the highest risk for rapid and severe curve progression?
Correct Answer & Explanation
. Unilateral unsegmented bar with a contralateral fully segmented hemivertebra
Explanation
A unilateral unsegmented bar with a contralateral fully segmented hemivertebra has the highest rate of progression (often exceeding 5-10 degrees per year). This occurs because growth is tethered on the concave side while unchecked growth continues on the convex side.
Question 7051
Topic: 6. Spine
Scoliosis is the most common musculoskeletal manifestation of Neurofibromatosis Type 1 (NF1). When evaluating an NF1 patient with a progressive spinal deformity, which combination of radiographic features is pathognomonic for "dystrophic" scoliosis?
Correct Answer & Explanation
. Penciling of the ribs, vertebral scalloping, and dural ectasia
Explanation
Dystrophic scoliosis in NF1 is characterized by short, sharp, angular curves. Classic radiographic features include "penciling" (thinning) of the ribs, posterior vertebral body scalloping, severe apical rotation, and dural ectasia. These curves are highly progressive and usually require combined anterior and posterior fusion.
Question 7052
Topic: 6. Spine
A 55-year-old male with long-standing ankylosing spondylitis sustains an extension-distraction fracture through the C6-C7 disc space. Following posterior instrumentation and fusion, he experiences an unexpected postoperative neurological decline in the recovery room. What is the most likely cause of this complication?
Correct Answer & Explanation
. Epidural hematoma
Explanation
Patients with ankylosing spondylitis are at a significantly higher risk for epidural hematomas following spinal trauma and subsequent surgery compared to the general population. This is due to altered epidural venous plexus dynamics, bleeding from fractured ossified ligaments, and the highly vascular nature of the inflammatory bone.
Question 7053
Topic: 6. Spine
A 14-year-old male with non-ambulatory spastic cerebral palsy presents with a progressive 85-degree thoracolumbar scoliosis and severe pelvic obliquity. Posterior spinal fusion to the pelvis is planned. What is the primary biomechanical advantage of utilizing S2-alar-iliac (S2AI) or iliac screws over traditional Galveston rod techniques?
Correct Answer & Explanation
. Improved rotational stability and pullout strength
Explanation
S2AI and iliac screws offer superior biomechanical pullout strength and rotational stability compared to the Galveston technique. They also eliminate the need for complex, three-dimensional rod bending and reduce the incidence of hardware prominence.
Question 7054
Topic: 6. Spine
A 28-year-old male with HLA-B27 positive ankylosing spondylitis presents with progressive sacroiliitis and morning stiffness. He has failed a 3-month trial of continuous treatment with two different nonsteroidal anti-inflammatory drugs (NSAIDs). According to current clinical guidelines, what is the most appropriate next pharmacological intervention?
Correct Answer & Explanation
. Tumor necrosis factor (TNF) alpha inhibitor
Explanation
For patients with active axial spondyloarthritis who have an inadequate response to NSAIDs, the next recommended step is biologic therapy, typically a TNF-alpha inhibitor (e.g., etanercept, adalimumab). Conventional disease-modifying antirheumatic drugs (DMARDs) like methotrexate lack efficacy for purely axial disease.
Question 7055
Topic: 6. Spine
A 35-year-old male with a history of intravenous drug use presents with acute onset of severe low back pain, fever, and progressive bilateral lower extremity weakness. MRI shows discitis and osteomyelitis involving L4-L5 with an epidural abscess. White blood cell count is elevated, and ESR/CRP are significantly raised. What is the most critical initial management step after diagnosis?
Correct Answer & Explanation
. Surgical decompression and debridement of the infection
Explanation
Given the presence of progressive neurological deficits (bilateral lower extremity weakness) in the setting of an epidural abscess secondary to discitis and osteomyelitis, emergent surgical decompression and debridement of the infection is the most critical initial management step. This is necessary to relieve spinal cord or cauda equina compression and prevent irreversible neurological damage. While IV antibiotics are crucial, they are often initiated pre-operatively but cannot resolve mass effect. Percutaneous drainage may be an option for smaller, non-compressive abscesses without neurological compromise. Corticosteroids are not typically used for infectious epidural abscesses and may be detrimental. Oral antibiotics are inadequate for severe infections like this.
Question 7056
Topic: Thoracolumbar Spine & Deformity
Which of the following is an accepted indication for surgical treatment of scoliosis in an adolescent with idiopathic scoliosis?
Correct Answer & Explanation
. Skeletally immature patient with a thoracic curve exceeding 45-50 degrees.
Explanation
Surgical treatment for adolescent idiopathic scoliosis is generally indicated for skeletally immature patients with progressive curves or curves that are already large. A thoracic curve exceeding 45-50 degrees (or lumbar/thoracolumbar curves exceeding 40-45 degrees) in a skeletally immature patient is a common indication for surgery to prevent further progression and manage cosmetic deformity. Smaller curves (15-25 degrees) in skeletally immature patients are typically observed or braced. A 25-degree curve in a skeletally mature patient or an asymptomatic 30-degree curve in a mature patient would typically be observed, as progression is less likely after skeletal maturity. Curve progression criteria for bracing often apply to 20-40 degree curves, but surgery is for larger, progressive curves.
Question 7057
Topic: 6. Spine
Which of the following describes the 'safe zone' for anterior screw placement into the vertebral body during pedicle screw fixation of the lumbar spine?
Correct Answer & Explanation
. Along the superior cortical border of the pedicle and into the anterior two-thirds of the vertebral body.
Explanation
The 'safe zone' for pedicle screw placement typically involves directing the screw along the superior cortical border of the pedicle and aiming it toward the anterior two-thirds of the vertebral body. This trajectory helps ensure maximum purchase and minimizes the risk of neural (medial breach) or vascular (anterior breach) injury. Angulation should be medial, but the specific degree varies. Aiming for the center of the vertebral body on AP view is important, but the superior cortical border of the pedicle is the entry point reference. Parallel to the superior endplate ensures length but doesn't define the entire trajectory or safety.
Question 7058
Topic: 6. Spine
A 65-year-old man complains of progressive clumsiness in his hands and difficulty with fine motor tasks, such as buttoning his shirt. Physical examination reveals a positive finger escape sign and a positive Hoffmann reflex. These findings are most indicative of dysfunction in which of the following anatomical structures?
Correct Answer & Explanation
. Corticospinal tracts of the cervical spinal cord
Explanation
The Hoffmann reflex and finger escape sign are upper motor neuron signs indicative of cervical myelopathy. They represent compression or dysfunction of the descending corticospinal tracts within the spinal cord.
Question 7059
Topic: 6. Spine
A 72-year-old male presents with deteriorating handwriting, frequent tripping, and bilateral hand numbness. Examination reveals a positive Hoffmann sign and hyperreflexia in the lower extremities. MRI confirms severe cervical cord compression. Which of the following MRI findings is the strongest predictor of permanent neurological deficits and poor post-surgical recovery?
Correct Answer & Explanation
. Focal hypointensity on T1-weighted MRI within the cord
Explanation
Focal hypointensity within the spinal cord on T1-weighted MRI indicates cystic necrosis or myelomalacia and represents irreversible damage. It is a much stronger predictor of poor neurological recovery in cervical spondylotic myelopathy than T2 hyperintensity alone.
Question 7060
Topic: 6. Spine
A 68-year-old male presents with bilateral hand clumsiness, difficulty buttoning his shirts, and frequent tripping. Neurological exam reveals a positive Hoffmann's sign and an inverted supinator reflex. The inverted supinator reflex best localizes the compressive spinal cord pathology to which cervical level?
Correct Answer & Explanation
. C5-C6
Explanation
The inverted supinator (brachioradialis) reflex localizes the compressive lesion to the C5-C6 spinal level. It manifests as a diminished brachioradialis reflex (C6 lower motor neuron lesion) with simultaneous hyperactive finger flexion (C8 upper motor neuron disinhibition).
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