This practice set contains high-yield board review questions covering key concepts in 6. Spine. Each clinical scenario is designed to test your diagnostic and management skills relevant to this subspecialty.
Question 4981
Topic: 6. Spine
A 54-year-old man presents with progressive clumsiness in his hands and a feeling of unsteadiness while walking over the past 6 months. Examination reveals hyperreflexia in the lower extremities, a positive Hoffmann sign bilaterally, and an inverted brachioradialis reflex. MRI of the cervical spine shows severe stenosis with cord signal change at C4-C5.
Without surgical intervention, what is the most likely natural history of his condition?
Correct Answer & Explanation
. Stepwise progression of neurologic deterioration
Explanation
The clinical presentation is consistent with cervical spondylotic myelopathy (CSM). The natural history of CSM typically involves a stepwise progression of neurologic deterioration, with periods of stable symptoms followed by acute declines. Spontaneous improvement is rare. Surgical decompression is generally recommended for moderate to severe or progressive myelopathy to halt disease progression.
Question 4982
Topic: 6. Spine
A 50-year-old man with a history of intravenous drug use presents with severe lower back pain, fever, and progressive weakness in both legs over the last 48 hours. Laboratory studies show an elevated erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). MRI reveals a fluid collection in the epidural space at L3-L4 compressing the thecal sac.
Which of the following is the most likely causative organism?
Correct Answer & Explanation
. Staphylococcus aureus
Explanation
Spinal epidural abscesses present with a classic triad of back pain, fever, and neurologic deficits. Intravenous drug use, diabetes mellitus, and immunocompromised states are significant risk factors. The most common causative organism overall, including in intravenous drug users, is Staphylococcus aureus. Pseudomonas is also seen in IV drug users but remains less common than S. aureus.
Question 4983
Topic: 6. Spine
A 35-year-old man falls from a roof and sustains a T12 burst fracture. He is neurologically intact on examination. CT of the spine shows 40% loss of anterior vertebral body height, 15 degrees of local kyphosis, and no evidence of posterior ligamentous complex (PLC) injury. MRI confirms the PLC is intact. According to the Thoracolumbar Injury Classification and Severity (TLICS) score, what is the recommended treatment?
Correct Answer & Explanation
. Nonoperative management with a thoracolumbosacral orthosis (TLSO)
Explanation
The Thoracolumbar Injury Classification and Severity (TLICS) system assigns points based on injury morphology, neurologic status, and posterior ligamentous complex (PLC) integrity. A burst fracture (2 points), neurologically intact status (0 points), and intact PLC (0 points) gives a total TLICS score of 2. A score of 3 or less is typically treated nonoperatively with an orthosis (e.g., TLSO) and early mobilization. Scores of 4 represent a gray area, while scores of 5 or more are considered surgical indications.
Question 4984
Topic: 6. Spine
A 45-year-old man presents with acute right anterior thigh pain and weakness in knee extension following a lifting injury. Physical examination reveals a diminished right patellar reflex and a positive femoral nerve stretch test. MRI of the lumbar spine reveals a large, far lateral (extraforaminal) disc herniation at the L4-L5 level on the right. Which of the following nerve roots is most likely being compressed?
Correct Answer & Explanation
. Exiting L4
Explanation
In the lumbar spine, a far lateral (extraforaminal) disc herniation compresses the exiting nerve root at that specific level. Therefore, an L4-L5 far lateral disc herniation will compress the exiting L4 nerve root, leading to L4 radiculopathy (anterior thigh pain, weak quadriceps, diminished patellar reflex). Conversely, a classic paracentral disc herniation at the L4-L5 level typically spares the exiting L4 root and compresses the traversing L5 nerve root.
Question 4985
Topic: 6. Spine
A 62-year-old man with a 30-year history of ankylosing spondylitis presents to the emergency department with severe back pain after a mechanical fall from standing height. Neurologic examination is unremarkable. Radiographs and CT scans reveal a transverse fracture through the T10-T11 disc space extending through the fused posterior elements.
What is the most appropriate management for this patient?
Correct Answer & Explanation
. Long-segment posterior spinal instrumentation and fusion
Explanation
Patients with ankylosing spondylitis have rigidly fused spines that act as long lever arms. Even low-energy trauma can cause highly unstable, three-column 'chalk stick' fractures. Because of the altered biomechanics and tremendous shear forces across the fracture site, conservative management or short-segment fixation carries an unacceptably high risk of nonunion, displacement, and secondary neurologic injury. The standard of care is long-segment posterior spinal instrumentation and fusion (typically 2 to 3 levels above and below the fracture).
Question 4986
Topic: 6. Spine
A 16-year-old male gymnast has a 9-month history of localized lower back pain that worsens with extension. He has no radicular symptoms and his neurologic examination is normal. He has failed a comprehensive regimen of rest, NSAIDs, physical therapy, and a trial of bracing. Radiographs reveal a Grade 1 isthmic spondylolisthesis at L5-S1. What is the most appropriate surgical intervention?
Correct Answer & Explanation
. Posterolateral L5-S1 spinal fusion in situ
Explanation
In a skeletally immature or young adult patient with symptomatic low-grade (Grade 1 or 2) isthmic spondylolisthesis at L5-S1 that has failed nonoperative management, the gold standard surgical treatment is an uninstrumented or instrumented L5-S1 posterolateral fusion in situ. Direct pars repair is generally contraindicated at L5-S1 due to high sheer forces and poor biomechanics, leading to high failure rates (it is more appropriate for L4 and above). Laminectomy alone without fusion is contraindicated as it exacerbates instability.
Question 4987
Topic: 6. Spine
A 65-year-old man presents with deteriorating handwriting, frequent dropping of objects, and a broad-based, unsteady gait. Physical examination reveals an inverted brachioradialis reflex. This highly specific finding is indicative of pathology at which of the following spinal levels?
Correct Answer & Explanation
. C5-C6
Explanation
The patient's symptoms and examination are classic for cervical spondylotic myelopathy (CSM). The inverted brachioradialis reflex is elicited by tapping the brachioradialis tendon; a positive sign is the absence of the normal response (elbow flexion/radial deviation) combined with paradoxical spontaneous flexion of the fingers. It is a highly specific upper motor neuron sign indicative of spinal cord compression at the C5-C6 level, as it demonstrates lower motor neuron dysfunction at C5/C6 and upper motor neuron hyperreflexia below this level.
Question 4988
Topic: 6. Spine
A 54-year-old man with poorly controlled diabetes mellitus presents with severe, unrelenting mid-back pain, fevers, and new-onset bilateral leg weakness that has progressed over the last 12 hours. MRI with contrast reveals a large, dorsally located epidural collection from T6 to T9 with significant cord compression. What is the most appropriate next step in management?
Correct Answer & Explanation
. Emergent posterior decompressive laminectomy and debridement
Explanation
The patient has a spinal epidural abscess (SEA) causing progressive neurologic deficit (bilateral leg weakness). This is an orthopedic/neurosurgical emergency. Medical management (antibiotics alone) is only indicated in patients without neurologic deficits, those who are prohibitively high risk for surgery, or those with complete paralysis lasting >48-72 hours. Because the abscess is dorsally located, an emergent posterior decompressive laminectomy with debridement and culture is the procedure of choice.
Question 4989
Topic: 6. Spine
An 8-year-old boy with Down syndrome is brought in by his parents for medical clearance to participate in gymnastics. He is completely asymptomatic and his neurologic exam is normal. Flexion-extension radiographs of the cervical spine demonstrate an atlantodens interval (ADI) of 7 mm. What is the most appropriate recommendation?
Correct Answer & Explanation
. Restriction from high-risk and contact sports, with close clinical observation
Explanation
In children, an atlantodens interval (ADI) up to 4-5 mm can be considered normal. In patients with Down syndrome, an ADI between 5 mm and 9 mm in the absence of neurologic symptoms indicates mild to moderate atlantoaxial instability. These patients do not require prophylactic surgery but should be restricted from contact sports and activities that place the cervical spine at risk (like gymnastics, diving, or rugby) and monitored closely. Surgical fusion is indicated if the patient develops neurologic symptoms, the ADI exceeds 10 mm, or the space available for the cord (SAC) is less than 14 mm.
Question 4990
Topic: 6. Spine
A 40-year-old man presents to the emergency department with acute onset of bilateral lower extremity weakness, perineal numbness, and sexual impotence following a heavy lifting incident. Examination reveals symmetrical 3/5 weakness in bilateral hip flexors, knee extensors, and ankle dorsiflexors. Deep tendon reflexes at the knees and ankles are hyperactive (3+). Anal sphincter tone is absent. Which of the following is the most likely diagnosis?
Correct Answer & Explanation
. Conus medullaris syndrome
Explanation
The presentation of sudden, symmetrical, bilateral lower extremity weakness, early sphincter dysfunction, impotence, and mixed upper motor neuron (hyperreflexia) and lower motor neuron signs (absent anal tone) points to Conus medullaris syndrome. The conus medullaris is the terminal end of the spinal cord (usually L1-L2) and contains both UMNs and LMNs. Cauda equina syndrome, in contrast, involves only lower motor nerve roots and classically presents with asymmetrical, unilateral or bilateral radicular pain, hyporeflexia, and a later onset of bowel/bladder dysfunction.
Question 4991
Topic: Thoracolumbar Spine & Deformity
A 65-year-old female presents with progressive low back pain and difficulty standing upright. She has to bend her knees to look straight ahead. Radiographic analysis reveals a pelvic incidence (PI) of 60 degrees, a lumbar lordosis (LL) of 25 degrees, and a sagittal vertical axis (SVA) of +12 cm. She has failed all conservative management. What is the most critical radiographic goal of her surgical correction?
Correct Answer & Explanation
. Restoration of Lumbar Lordosis (LL) to within 10 degrees of Pelvic Incidence (PI)
Explanation
In adult spinal deformity, restoring sagittal balance is highly correlated with improved patient outcomes (HRQOL scores). The accepted radiographic goals defined by the Scoliosis Research Society (SRS) include maintaining a Sagittal Vertical Axis (SVA) < 5 cm, a Pelvic Tilt (PT) < 20 degrees, and a PI-LL mismatch within +/- 9 degrees. Achieving a PI-LL mismatch of less than 10 degrees is crucial to restoring global sagittal alignment and reducing compensatory mechanisms like knee flexion.
Question 4992
Topic: 6. Spine
A 70-year-old male with progressive gait clumsiness and hand dexterity issues undergoes a C3-C6 cervical laminectomy and instrumented fusion. On postoperative day 2, he reports isolated profound bilateral deltoid and biceps weakness (Medical Research Council grade 2/5). Sensation and lower extremity function remain completely unchanged. Which of the following is the most likely etiology of this patient's new neurologic deficit?
Correct Answer & Explanation
. Iatrogenic C5 nerve root traction
Explanation
C5 palsy is a known complication following cervical decompression, classically seen after a posterior laminectomy and fusion due to the posterior drift of the spinal cord. The C5 nerve root has a short, horizontal course and can undergo stretch/traction when the spinal cord shifts posteriorly following decompression (the 'tethering effect'). Presentation is typically isolated deltoid and/or biceps weakness postoperatively without long tract signs. An epidural hematoma would typically present with a broader deterioration including global myelopathy.
Question 4993
Topic: Thoracolumbar Spine & Deformity
A 35-year-old construction worker falls from a 15-foot scaffolding, sustaining severe middle back pain. Neurological examination is intact bilaterally (ASIA E). A CT scan of the thoracic spine demonstrates a T12 burst fracture with 40% loss of anterior vertebral body height, 15 degrees of focal kyphosis, and a vertical splitting fracture of the lamina. An MRI reveals fluid signal and disruption of the posterior ligamentous complex (PLC). Based on the Thoracolumbar Injury Classification and Severity (TLICS) score, what is the most appropriate management?
Correct Answer & Explanation
. Surgical stabilization
Explanation
The Thoracolumbar Injury Classification and Severity (TLICS) score evaluates three parameters: fracture morphology, neurologic status, and posterior ligamentous complex (PLC) integrity. Burst fracture = 2 points. Intact neurologic status = 0 points. Disrupted PLC = 3 points. The total score is 5. A TLICS score of > 4 is an indication for surgical stabilization. A score of 3 or less is typically treated non-surgically, while 4 is indeterminate.
Question 4994
Topic: Thoracolumbar Spine & Deformity
A 14-year-old female gymnast presents with a 6-month history of mechanical low back pain. Radiographs demonstrate a Grade II L5-S1 spondylolisthesis. Advanced imaging confirms bilateral pars interarticularis defects at L5. She has failed 6 months of physical therapy, bracing, and NSAIDs. Her pain restricts her activities of daily living and sports. What is the most appropriate surgical treatment?
Correct Answer & Explanation
. L5-S1 posterolateral fusion with or without interbody fusion
Explanation
In symptomatic adolescent isthmic spondylolisthesis (Grade I or II) that has failed extensive conservative management, L5-S1 fusion (posterolateral with or without interbody) is the gold standard. Direct pars repair (e.g., Buck's or Scott's wiring) is generally reserved for patients with pars defects without significant slip, and is more commonly performed at L4 or above, as L5 is technically difficult and less reliable for direct repair. Artificial disc replacement is contraindicated in the presence of instability and pars defects.
Question 4995
Topic: Cervical Spine
An 82-year-old male falls from a standing height. He has severe neck pain but a normal neurologic examination. CT scan reveals a Type II odontoid fracture with 2 mm of posterior displacement. Comorbidities include severe COPD, diabetes mellitus, and severe osteoporosis. Which of the following treatments provides the best balance of safety and efficacy for this specific patient?
Correct Answer & Explanation
. Rigid cervical collar immobilization
Explanation
Type II odontoid fractures in the elderly have a high nonunion rate, but surgical intervention carries significant morbidity and mortality, especially with severe comorbidities like COPD. Halo vest immobilization in the elderly is associated with unacceptably high morbidity and mortality (e.g., respiratory complications, pin site infections). Studies (including the AOSpine North America Geriatric Odontoid Fracture Initiative) have shown that rigid cervical collar immobilization is a viable, safe option, often leading to a stable fibrous nonunion with satisfactory clinical outcomes. Anterior screw fixation is contraindicated in the presence of severe osteoporosis.
Question 4996
Topic: 6. Spine
A 45-year-old male with a long-standing history of ankylosing spondylitis presents to the emergency department after a low-speed motor vehicle collision. He complains of new-onset neck pain. Neurologic examination is unremarkable. Standard AP, lateral, and open-mouth odontoid plain radiographs are negative for fracture or dislocation. What is the most appropriate next step in the management of this patient?
Correct Answer & Explanation
. CT scan of the entire cervical spine
Explanation
Patients with ankylosing spondylitis (AS) have a rigid, osteopenic spine that acts as a long lever arm. They are highly susceptible to unstable fractures even from minor trauma. Plain radiographs are notoriously unreliable in AS due to altered anatomy, osteopenia, and superimposition of the shoulders. A CT scan of the entire cervical (or whole) spine is mandatory in any AS patient presenting with neck or back pain following trauma, even if plain films are interpreted as negative. Flexion-extension views are contraindicated in the acute trauma setting with potential occult unstable fractures.
Question 4997
Topic: 6. Spine
A 60-year-old diabetic patient presents with acute worsening back pain, low-grade fevers, and progressive bilateral lower extremity weakness over the last 48 hours. ESR and CRP are markedly elevated. MRI with contrast shows L3-L4 discitis/osteomyelitis with an associated anterior epidural abscess causing severe thecal sac compression. Blood cultures are pending. Examination reveals 3/5 strength in hip flexion and knee extension bilaterally. What is the most appropriate immediate management?
Correct Answer & Explanation
. Emergent open surgical decompression and debridement
Explanation
This patient has a spinal epidural abscess presenting with an acute, progressive neurologic deficit (3/5 strength). While broad-spectrum antibiotics and CT-guided biopsy are appropriate for uncomplicated discitis/osteomyelitis without neurologic compromise, the presence of an active neurologic deficit and significant epidural compression on MRI mandates emergent surgical decompression and debridement. Medical management alone in the face of progressive neurologic deficits carries an unacceptably high risk of irreversible paralysis.
Question 4998
Topic: 6. Spine
A 72-year-old male presents with bilateral leg pain and cramping that worsens with walking. The pain reliably improves when he sits down or leans over a shopping cart. To distinguish between neurogenic claudication and vascular claudication, the physician performs a stationary bicycle test (van Gelderen bicycle test). Which of the following findings during the test is most characteristic of neurogenic claudication?
Correct Answer & Explanation
. Pain is relieved or prevented when pedaling in a forward-flexed posture
Explanation
The stationary bicycle test (van Gelderen bicycle test) differentiates neurogenic claudication (from lumbar spinal stenosis) from vascular claudication. Patients with neurogenic claudication typically experience relief or can pedal substantially further when leaning forward in a flexed posture. Spinal flexion increases the cross-sectional area of the spinal canal and neural foramina, relieving compression. In contrast, patients with vascular claudication experience ischemic pain related to muscle workload, and the onset of pain will occur at a consistent workload/distance regardless of spinal posture.
Question 4999
Topic: Thoracolumbar Spine & Deformity
A 65-year-old woman presents with severe low back pain and leaning forward when walking. Standing lateral radiographs show a Pelvic Incidence (PI) of 60 degrees, Pelvic Tilt (PT) of 35 degrees, and Lumbar Lordosis (LL) of 20 degrees. Her Sagittal Vertical Axis (SVA) is +12 cm. What is the goal of surgical correction for this patient based on the SRS-Schwab classification?
Correct Answer & Explanation
. LL = 60 degrees, PT < 20 degrees, SVA < 5 cm
Explanation
Based on the SRS-Schwab classification for adult spinal deformity, surgical correction goals to achieve ideal sagittal alignment include matching the Lumbar Lordosis (LL) to the Pelvic Incidence (PI) within 9 degrees (PI-LL < +/- 9 degrees). For a PI of 60 degrees, the target LL should be approximately 60 degrees. Additional goals include restoring Pelvic Tilt (PT) to < 20 degrees and Sagittal Vertical Axis (SVA) to < 5 cm. Option B accurately reflects all these goals.
Question 5000
Topic: Cervical Spine
A 78-year-old man presents with neck pain after a ground-level fall. CT scan reveals a Type II odontoid fracture with 3 mm of posterior displacement. He is neurologically intact. He has a history of severe COPD, congestive heart failure, and coronary artery disease. What is the most appropriate management?
Correct Answer & Explanation
. Hard cervical collar
Explanation
In the elderly population, particularly octogenarians or those with severe comorbidities, Type II odontoid fractures are associated with high morbidity and mortality regardless of treatment. Rigid immobilization with a halo vest is poorly tolerated and associated with life-threatening complications (e.g., aspiration, pin site infection, pneumonia) without a significant improvement in union rates. While posterior C1-C2 fusion provides high union rates, this patient is a poor surgical candidate due to his severe comorbidities. Nonoperative management with a hard cervical collar aims for fibrous nonunion and symptom control while minimizing morbidity, making it the most appropriate choice.
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