This practice set contains high-yield board review questions covering key concepts in 6. Spine. Each clinical scenario is designed to test your diagnostic and management skills relevant to this subspecialty.
Question 401
Topic: 6. Spine
A 32-year-old woman presents with severe back pain, bilateral sciatica, saddle anesthesia, and urinary retention. MRI confirms a massive L4-L5 disc herniation compressing the thecal sac. For optimal prognostic neurologic recovery, emergent surgical decompression should ideally be performed within:
Correct Answer & Explanation
. 48 hours
Explanation
Cauda equina syndrome is a surgical emergency. Decompression performed within 48 hours is associated with a significantly higher rate of resolution of sensory and motor deficits, as well as bladder and bowel dysfunction.
Question 402
Topic: 6. Spine
A 60-year-old man with neurogenic claudication finds significant relief of his leg pain when leaning forward on a shopping cart. This postural relief is anatomically explained by:
Correct Answer & Explanation
. An increase in the cross-sectional area of the spinal canal
Explanation
Flexion of the lumbar spine stretches the ligamentum flavum (making it thinner) and opens the interlaminar space, thereby increasing the cross-sectional area of the spinal canal and relieving pressure on the nerve roots.
Question 403
Topic: 6. Spine
In a patient with a suspected far lateral (extraforaminal) disc herniation at the L4-L5 level, which nerve root is most directly compressed?
Correct Answer & Explanation
. L4
Explanation
A far lateral (extraforaminal) disc herniation impinges the exiting nerve root at that level. At L4-L5, the exiting root is L4, whereas a standard posterolateral herniation at L4-L5 would impinge the traversing L5 root.
Question 404
Topic: 6. Spine
An 80-year-old man with a history of prostate cancer presents with severe, unremitting low back pain that is worse at night. Anteroposterior plain radiographs reveal an absent right pedicle at L3. This radiographic finding is classically referred to as the:
Correct Answer & Explanation
. Winking owl sign
Explanation
The "winking owl" sign occurs on an AP radiograph when one pedicle is destroyed (often by lytic metastatic disease), leaving only the contralateral pedicle visible, resembling a winking owl.
Question 405
Topic: 6. Spine
A 65-year-old patient with long-standing ankylosing spondylitis sustains a minor fall. He complains of new-onset mechanical neck pain but exhibits no neurologic deficits. Plain radiographs of the cervical spine are obscured by the shoulders and appear unremarkable. The most appropriate next step in management is:
Correct Answer & Explanation
. CT scan of the entire cervical spine
Explanation
Patients with ankylosing spondylitis have a highly rigid spine, making them highly susceptible to unstable fractures even from minor trauma. A CT scan is mandatory as plain radiographs often miss these fractures.
Question 406
Topic: 6. Spine
A 50-year-old woman presents with worsening clumsiness in her hands and difficulty maintaining balance while walking. Examination reveals a positive Hoffman's sign, hyperreflexia in the lower extremities, and a broad-based gait. The most likely diagnosis is:
Correct Answer & Explanation
. Cervical spondylotic myelopathy
Explanation
The triad of upper extremity clumsiness, gait instability, and upper motor neuron signs (Hoffman's, hyperreflexia) is the classic presentation of cervical spondylotic myelopathy.
Question 407
Topic: Cervical Spine
The Rule of Spence is utilized to evaluate the integrity of the transverse ligament in C1 ring (Jefferson) fractures. A ruptured transverse ligament is indicated if the combined lateral mass overhang on an open-mouth odontoid radiograph exceeds:
Correct Answer & Explanation
. 6.9 mm
Explanation
According to the Rule of Spence, a combined overhang of the lateral masses of C1 on C2 of more than 6.9 mm indicates a rupture of the transverse alar ligament, signifying instability.
Question 408
Topic: 6. Spine
A 72-year-old woman falls and strikes her chin, forcing her neck into severe hyperextension. She develops profound motor weakness in her arms and hands, but retains relatively preserved motor strength in her legs. Which incomplete spinal cord syndrome does this represent?
Correct Answer & Explanation
. Central cord syndrome
Explanation
Central cord syndrome typically occurs after a hyperextension injury in patients with preexisting cervical stenosis. It predominantly affects the centrally located cervical tracts, causing upper extremity weakness out of proportion to the lower extremities.
Question 409
Topic: Thoracolumbar Spine & Deformity
A 25-year-old male presents with severe mechanical back pain. Standing lateral lumbar radiographs reveal a pars interarticularis defect with a 35% anterior translation of L5 on S1. According to the Meyerding classification, this represents:
Correct Answer & Explanation
. Grade II spondylolisthesis
Explanation
The Meyerding classification grades the percentage of slip: Grade I (0-25%), Grade II (26-50%), Grade III (51-75%), Grade IV (76-100%), and Grade V (>100%, spondyloptosis). A 35% slip is Grade II.
Question 410
Topic: 6. Spine
A 40-year-old male sustains a stab wound to the right side of his thoracic spine. He subsequently exhibits loss of ipsilateral motor function and proprioception, and loss of contralateral pain and temperature sensation below the lesion level. This presentation is characteristic of:
Correct Answer & Explanation
. Brown-Sequard syndrome
Explanation
Brown-Sequard syndrome results from spinal cord hemisection. It features ipsilateral loss of motor function (corticospinal tract) and dorsal column function (proprioception), with contralateral loss of spinothalamic function (pain/temperature).
Question 411
Topic: 6. Spine
In a patient suffering from central lumbar spinal stenosis, the hypertrophy of which specific posterior ligament significantly contributes to the dorsal narrowing of the spinal canal?
Correct Answer & Explanation
. Ligamentum flavum
Explanation
The ligamentum flavum lines the posterior aspect of the spinal canal. Its hypertrophy and buckling with age, along with facet arthropathy, are primary contributors to acquired degenerative central spinal stenosis.
Question 412
Topic: 6. Spine
A patient presenting with an acute posterolateral disc herniation at the C5-C6 level will most likely exhibit weakness in which of the following actions?
Correct Answer & Explanation
. Wrist extension
Explanation
A C5-C6 disc herniation compresses the exiting C6 nerve root. The C6 root supplies the extensor carpi radialis longus and brevis (wrist extension) and the biceps/brachioradialis (elbow flexion).
Question 413
Topic: 6. Spine
Which of the following physical examination maneuvers is considered a Waddell sign, indicating a non-organic component to a patient's low back pain presentation?
Correct Answer & Explanation
. Severe pain behavior elicited upon simulated axial downward loading on the skull
Explanation
Waddell signs test for non-organic (psychological or exaggerated) pain. Simulated axial loading of the skull causing lower back pain is a classic non-organic sign, as this maneuver does not physiologically load the lumbar spine.
Question 414
Topic: Thoracolumbar Spine & Deformity
A 14-year-old female gymnast presents with persistent, activity-related lower back pain. Oblique lumbar radiographs reveal a "collared Scotty dog" appearance. This radiographic sign specifically indicates:
Correct Answer & Explanation
. Spondylolysis
Explanation
The "collared Scotty dog" sign seen on oblique lumbar radiographs represents a defect or fracture in the pars interarticularis, which is the definition of spondylolysis.
Question 415
Topic: Thoracolumbar Spine & Deformity
Following a motor vehicle collision, a 30-year-old man sustains a burst fracture of L1. According to the Denis three-column concept of spinal stability, the middle column comprises the:
Correct Answer & Explanation
. Posterior half of the vertebral body, posterior annulus, and posterior longitudinal ligament
Explanation
In the Denis three-column theory, the middle column consists of the posterior half of the vertebral body, the posterior portion of the annulus fibrosus, and the posterior longitudinal ligament. Disruption of this column characterizes a burst fracture.
Question 416
Topic: 6. Spine
A 55-year-old man presents with progressive clumsiness in his hands, frequent dropping of objects, and a wide-based gait. Examination reveals hyperreflexia in the lower extremities and a positive Hoffmann sign bilaterally. Which of the following is the most appropriate initial diagnostic imaging modality?
Correct Answer & Explanation
. MRI of the cervical spine
Explanation
The patient's symptoms and signs (clumsiness, wide-based gait, hyperreflexia, positive Hoffmann sign) are classic for cervical spondylotic myelopathy. MRI of the cervical spine is the gold standard for evaluating spinal cord compression.
Question 417
Topic: 6. Spine
A 45-year-old man develops acute right leg pain radiating to the anterior thigh following heavy lifting. Physical examination demonstrates weakness in knee extension and a diminished patellar tendon reflex. An MRI of the lumbar spine reveals a far lateral disc herniation at the L4-L5 level. Which nerve root is most likely compressed?
Correct Answer & Explanation
. L4
Explanation
In the lumbar spine, a far lateral (extraforaminal) disc herniation compresses the exiting nerve root at that level. Therefore, a far lateral disc at L4-L5 compresses the L4 nerve root, leading to anterior thigh pain, quadriceps weakness, and a decreased patellar reflex.
Question 418
Topic: Thoracolumbar Spine & Deformity
A 14-year-old female gymnast presents with progressive low back pain. Examination reveals a palpable step-off at the lumbosacral junction. Radiographs demonstrate a Grade 2 isthmic spondylolisthesis at L5-S1. Neurological examination is normal. What is the most appropriate initial management?
Correct Answer & Explanation
. Activity modification, physical therapy, and bracing
Explanation
Initial management of low-grade (Grade 1 and 2) isthmic spondylolisthesis without neurological deficits in an adolescent is conservative. This involves activity modification, physical therapy emphasizing core stabilization, and potentially bracing.
Question 419
Topic: 6. Spine
A 60-year-old man presents to the emergency department with severe acute lower back pain, bilateral sciatica, and perineal numbness. Which of the following clinical findings is the most sensitive indicator of cauda equina syndrome?
Correct Answer & Explanation
. Urinary retention with a post-void residual greater than 100-200 mL
Explanation
Urinary retention is the most consistent and sensitive finding in cauda equina syndrome. A normal post-void residual bladder volume effectively rules out the diagnosis in most cases.
Question 420
Topic: 6. Spine
A 35-year-old intravenous drug user presents with fever, severe focal mid-back pain, and elevated inflammatory markers. MRI reveals an anterior epidural abscess at T8. The empirical antibiotic regimen should primarily target which of the following microorganisms?
Correct Answer & Explanation
. Staphylococcus aureus
Explanation
Staphylococcus aureus is the most common causative organism in spinal epidural abscesses and vertebral osteomyelitis, particularly in intravenous drug users. Empirical coverage must include MRSA along with gram-negative coverage until cultures are finalized.
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