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Question 3761

Topic: 3. Adult Reconstruction (Hip & Knee)

Six months after a primary THA, a 55-year-old woman reports sharp, catching groin pain that occurs specifically when lifting her leg to get into a car or climbing stairs. Passive hip rotation is painless, but resisted straight leg raise reproduces her pain. Radiographs reveal an acetabular component placed in 45 degrees of inclination and 10 degrees of retroversion, with the anterior edge of the cup overhanging the bone.

What is the most likely diagnosis?

. Aseptic loosening of the acetabular cup
. Iliopsoas impingement
. Periprosthetic joint infection
. Heterotopic ossification
. Gluteus medius avulsion

Correct Answer & Explanation

. Iliopsoas impingement


Explanation

Iliopsoas impingement commonly presents as anterior groin pain with active hip flexion (e.g., getting into a car). It is often caused by an oversized or retroverted acetabular cup that overhangs the anterior rim, irritating the overlying psoas tendon.

Question 3762

Topic: 3. Adult Reconstruction (Hip & Knee)

A 55-year-old male presents with new-onset groin pain 6 years after undergoing a total hip arthroplasty with a metal-on-polyethylene bearing and a modular titanium stem with a cobalt-chromium head. Infection workup including aspiration is negative. MRI shows a solid/cystic mass in the periprosthetic soft tissues. What is the most likely pathophysiologic mechanism for this patient's condition?

. Galvanic corrosion at the stem-cement interface
. Macrophage-induced osteolysis from polyethylene wear debris
. Mechanically assisted crevice corrosion at the head-neck taper
. Type IV delayed hypersensitivity reaction to titanium
. Aseptic loosening of the acetabular component

Correct Answer & Explanation

. Mechanically assisted crevice corrosion at the head-neck taper


Explanation

This patient presents with an adverse local tissue reaction (ALTR) or pseudotumor despite having a metal-on-polyethylene articulation. This is classically caused by mechanically assisted crevice corrosion (trunnionosis) at the modular head-neck taper junction.

Question 3763

Topic: 3. Adult Reconstruction (Hip & Knee)

A 62-year-old female presents with chronic pain 2 years after a primary total hip arthroplasty. Serologic inflammatory markers (ESR and CRP) are equivocal. Aspiration is performed to rule out periprosthetic joint infection (PJI). Which of the following synovial fluid biomarkers provides the highest sensitivity and specificity for diagnosing PJI?

. Leukocyte esterase
. Interleukin-6 (IL-6)
. C-reactive protein (CRP)
. Procalcitonin
. Alpha-defensin

Correct Answer & Explanation

. Alpha-defensin


Explanation

Alpha-defensin is an antimicrobial peptide secreted by neutrophils with high accuracy for diagnosing PJI. It has demonstrated superior sensitivity and specificity compared to other synovial fluid markers, even in cases involving prior antibiotic use.

Question 3764

Topic: 3. Adult Reconstruction (Hip & Knee)

According to Lewinnek's classically described safe zone for total hip arthroplasty, what acetabular component orientation is recommended to minimize the risk of postoperative dislocation?

. 30 degrees of inclination (abduction) and 10 degrees of anteversion
. 40 degrees of inclination (abduction) and 15 degrees of anteversion
. 45 degrees of inclination (abduction) and 25 degrees of anteversion
. 50 degrees of inclination (abduction) and 20 degrees of anteversion
. 35 degrees of inclination (abduction) and 5 degrees of retroversion

Correct Answer & Explanation

. 40 degrees of inclination (abduction) and 15 degrees of anteversion


Explanation

Lewinnek established the historical safe zone for acetabular cup placement as 40 ± 10 degrees of inclination (abduction) and 15 ± 10 degrees of anteversion. Placing the cup within these parameters is associated with a reduced risk of instability.

Question 3765

Topic: 3. Adult Reconstruction (Hip & Knee)

A 78-year-old male sustains a fall 8 years following an uncemented total hip arthroplasty. Radiographs reveal a periprosthetic femur fracture around the middle of the femoral stem. The stem has subsided 2 cm compared to previous films, but the proximal femur demonstrates thick, excellent cortical bone stock. According to the Vancouver classification, what is the fracture type and the recommended surgical management?

. Vancouver B1; Open reduction and internal fixation with a locking plate
. Vancouver B2; Revision arthroplasty with a long extensively porous-coated or fluted tapered stem
. Vancouver B3; Proximal femoral replacement (megaprosthesis)
. Vancouver C; Open reduction and internal fixation bypassing the tip of the stem
. Vancouver A; Cerclage wiring of the greater trochanter

Correct Answer & Explanation

. Vancouver B2; Revision arthroplasty with a long extensively porous-coated or fluted tapered stem


Explanation

This is a Vancouver B2 fracture because it occurs around the stem, the stem is loose (subsided), and there is adequate bone stock remaining. The standard treatment is revision to a longer uncemented stem to achieve stable diaphyseal fixation.

Question 3766

Topic: 3. Adult Reconstruction (Hip & Knee)

When evaluating patients for metal-on-metal hip resurfacing arthroplasty, which of the following characteristics represents the most ideal candidate and is associated with the lowest long-term failure rates?

. A 60-year-old female with primary osteoarthritis
. A 50-year-old male with severe osteonecrosis and a 30% head involvement cyst
. A 45-year-old male with primary osteoarthritis and normal femoral head-neck anatomy
. A 40-year-old female with developmental dysplasia of the hip
. A 35-year-old male with end-stage renal disease and secondary arthritis

Correct Answer & Explanation

. A 45-year-old male with primary osteoarthritis and normal femoral head-neck anatomy


Explanation

The ideal candidate for hip resurfacing is a younger, active male (typically under 55) with primary osteoarthritis, good bone density, and normal femoral morphology. Females, patients with avascular necrosis or cysts, and those with poor bone quality have significantly higher failure rates.

Question 3767

Topic: Total Hip Arthroplasty (THA)

A 68-year-old man presents with recurrent posterior dislocations of his total hip arthroplasty (THA). He underwent a primary THA through a posterior approach 6 months ago. Radiographs demonstrate a well-fixed, uncemented acetabular cup with 40 degrees of inclination and 0 degrees of anteversion. The femoral stem is well-fixed with 15 degrees of anteversion.

To optimally stabilize this hip during revision surgery, the surgeon should aim to:

. Increase the cup inclination to 55 degrees
. Increase the cup anteversion to 20 degrees
. Decrease the femoral stem anteversion to 0 degrees
. Exchange the modular head for a shorter neck length
. Perform an anterior approach revision without altering components

Correct Answer & Explanation

. Increase the cup anteversion to 20 degrees


Explanation

This patient's recurrent posterior dislocations are primarily driven by inadequate acetabular cup anteversion (currently 0 degrees). The optimal 'safe zone' for acetabular component positioning is historically described by Lewinnek as 40 ± 10 degrees of inclination and 15 ± 10 degrees of anteversion. Increasing the cup anteversion to roughly 20 degrees will provide anterior coverage and prevent the femoral head from levering out posteriorly during flexion and internal rotation. Increasing inclination (Option A) increases edge-loading and risk of superior dislocation. Decreasing stem anteversion (Option C) or shortening the neck (Option D) would further increase the risk of posterior instability.

Question 3768

Topic: 3. Adult Reconstruction (Hip & Knee)

A 52-year-old highly active man underwent a total hip arthroplasty (THA) using a ceramic-on-ceramic bearing surface 3 years ago. He now complains of an audible squeaking noise from the hip while walking. He denies any pain, fevers, or limitation in his functional activities. Radiographs demonstrate well-fixed components with 45 degrees of cup inclination and 15 degrees of anteversion. Inflammatory markers are within normal limits. What is the most appropriate next step in management?

. Immediate revision of the bearing surfaces to metal-on-polyethylene
. Obtain serum cobalt and chromium levels
. Image-guided hip aspiration to rule out indolent infection
. Reassurance and observation
. Revision of the acetabular component to decrease anteversion

Correct Answer & Explanation

. Reassurance and observation


Explanation

Squeaking is a known complication of ceramic-on-ceramic bearing surfaces, with a reported incidence ranging from 1% to 10%. It is thought to be multifactorial, potentially related to microseparation, edge-loading, or disruption of fluid-film lubrication. In a patient who has an audible squeak but is completely asymptomatic (no pain) with well-fixed and well-positioned components, the standard of care is reassurance and observation. Revision surgery is reserved for patients with mechanical symptoms, component loosening, severe pain, or ceramic fracture.

Question 3769

Topic: 3. Adult Reconstruction (Hip & Knee)

A 60-year-old woman presents with progressive groin pain and a palpable anterior thigh mass 7 years after a metal-on-metal total hip arthroplasty. Her serum cobalt level is significantly elevated at 18 ppb. A Metal Artifact Reduction Sequence (MARS) MRI reveals a large cystic mass communicating with the hip joint.

If a biopsy of this periprosthetic tissue is performed, what is the expected predominant histological finding?

. Abundant polymorphonuclear leukocytes and intracellular bacteria
. Extensive macrophage infiltration with birefringent polyethylene wear debris
. Perivascular lymphocytic infiltrate and extensive tissue necrosis
. Benign neoplastic proliferation of synovial cells and subsynovial stroma
. Sheet-like proliferation of multinucleated giant cells and heavy hemosiderin deposition

Correct Answer & Explanation

. Perivascular lymphocytic infiltrate and extensive tissue necrosis


Explanation

The patient is presenting with an Adverse Local Tissue Reaction (ALTR), specifically an Aseptic Lymphocyte-dominated Vasculitis-Associated Lesion (ALVAL), secondary to metal wear debris from a metal-on-metal THA. Histologically, ALVAL is characterized by a perivascular lymphocytic infiltrate (suggesting a Type IV delayed hypersensitivity reaction to metal ions, particularly cobalt and chromium) and areas of extensive tissue necrosis. Option A describes an acute infection. Option B describes classic particle disease from polyethylene wear (macrophage-mediated osteolysis). Option D describes tenosynovial giant cell tumor (PVNS). Option E describes features seen in classic PVNS or severe mechanical metallosis, but ALVAL specifically features the perivascular lymphocytic infiltrate.

Question 3770

Topic: 3. Adult Reconstruction (Hip & Knee)

A 72-year-old man complains of chronic right hip pain 2 years after a primary total hip arthroplasty. He has not had any acute exacerbation but states the pain has been constant for the last 6 months. Laboratory studies reveal an ESR of 60 mm/hr and a CRP of 45 mg/L. Joint aspiration yields synovial fluid with 4,500 WBCs/µL (85% neutrophils), and an alpha-defensin test is positive. Radiographs show lucency around the femoral stem. Based on the Musculoskeletal Infection Society (MSIS) criteria, what is the most appropriate definitive surgical management?

. Intravenous antibiotics for 6 weeks followed by observation
. Open irrigation and debridement with modular component exchange
. Single-stage revision arthroplasty using antibiotic-loaded cement
. Two-stage revision arthroplasty utilizing an antibiotic spacer
. Suppressive oral antibiotics indefinitely without surgical intervention

Correct Answer & Explanation

. Two-stage revision arthroplasty utilizing an antibiotic spacer


Explanation

This patient meets the criteria for a chronic periprosthetic joint infection (PJI) of the hip. The infection is considered chronic as he is well beyond the acute postoperative period (typically defined as < 4 weeks) and the symptoms have been present for 6 months. According to current standards in North America, the gold standard treatment for a chronic PJI with a loose implant is a two-stage revision arthroplasty. This involves removal of all components and cement, thorough debridement, placement of an antibiotic-loaded cement spacer, and 6 weeks of targeted IV antibiotics before reimplantation. Irrigation and debridement with modular exchange (Option B) is reserved for acute postoperative or acute hematogenous infections.

Question 3771

Topic: 3. Adult Reconstruction (Hip & Knee)
A 38-year-old man on chronic high-dose systemic corticosteroids for systemic lupus erythematosus presents with bilateral groin pain. MRI reveals bilateral femoral head osteonecrosis. On the right, there is evidence of subchondral collapse (crescent sign) with mild flattening of the femoral head. On the left, there is a focal anterosuperior necrotic lesion without any subchondral collapse or head flattening. What is the most widely accepted surgical management for this patient?
. Bilateral core decompression
. Bilateral total hip arthroplasty
. Right total hip arthroplasty and left core decompression
. Right core decompression and left observation
. Bilateral vascularized free fibular grafting

Correct Answer & Explanation

. Right total hip arthroplasty and left core decompression


Explanation

The treatment of avascular necrosis (AVN) of the femoral head depends heavily on whether subchondral collapse has occurred. The left hip is pre-collapse (Steinberg/Ficat Stage I or II) and is best treated with a head-preserving procedure such as core decompression to relieve intraosseous pressure and promote revascularization. The right hip has progressed to subchondral collapse and flattening (Steinberg/Ficat Stage III or higher); core decompression is generally ineffective at this stage, and a total hip arthroplasty (THA) is the most reliable treatment to relieve pain and restore function.

Question 3772

Topic: Total Hip Arthroplasty (THA)

A 55-year-old woman complains of new-onset, sharp groin pain radiating to the anterior thigh 8 months after an uncomplicated primary total hip arthroplasty. The pain is worst when initiating movement, particularly when lifting her leg to get into a car or climbing stairs. Physical examination reveals severe pain with resisted active straight leg raise. A diagnostic anesthetic injection into the psoas bursa provides complete relief. Which of the following is the most common radiographic finding associated with this condition?

. Excessive acetabular retroversion
. Prominent anterior edge of the acetabular component
. Undersized and subsided femoral stem
. Excessive native femoral offset restoration
. Extensive heterotopic ossification of the abductor musculature

Correct Answer & Explanation

. Prominent anterior edge of the acetabular component


Explanation

The patient is experiencing classic symptoms of iliopsoas impingement post-THA. The primary clinical sign is pain with active hip flexion (resisted straight leg raise), often described as 'start-up' groin pain. The condition is definitively diagnosed when an image-guided anesthetic injection into the iliopsoas bursa relieves the symptoms. The most common underlying structural cause is an overhanging or prominent anterior rim of the acetabular cup, which mechanically irritates the iliopsoas tendon as it courses over the anterior brim of the pelvis.

Question 3773

Topic: 3. Adult Reconstruction (Hip & Knee)

A 78-year-old woman presents to the emergency department after a mechanical fall. She underwent a cementless total hip arthroplasty 10 years ago. Radiographs reveal a spiral fracture around the tip of the femoral stem, extending slightly distal to the tip. Comparison to previous films confirms the stem remains rigidly fixed with no signs of subsidence, loosening, or osteolysis.

According to the Vancouver classification, what is the standard treatment for this injury?

. Non-operative management with touch-down weight-bearing for 6 weeks
. Open reduction and internal fixation utilizing cerclage wires alone
. Open reduction and internal fixation with a laterally applied locking plate and cables
. Revision to a long uncemented diaphyseal-engaging stem with strut allograft
. Proximal femoral replacement

Correct Answer & Explanation

. Open reduction and internal fixation with a laterally applied locking plate and cables


Explanation

This is a Vancouver B1 periprosthetic femur fracture. The Vancouver classification is based on fracture location, implant stability, and bone quality. Type B fractures occur around or just distal to the tip of the stem. A B1 fracture is characterized by a well-fixed stem and adequate bone stock. The gold standard treatment for a Vancouver B1 fracture is open reduction and internal fixation (ORIF), typically using a laterally applied locking plate spanning the length of the femur with cerclage cables proximally and bicortical screws distally. Revision arthroplasty (Option D) is reserved for loose stems (Vancouver B2 or B3).

Question 3774

Topic: Total Hip Arthroplasty (THA)

A 65-year-old man presents with his third posterior dislocation of a total hip arthroplasty performed 6 months ago via a posterior approach. Radiographs reveal the acetabular component has 5 degrees of anteversion and 40 degrees of abduction. The femoral stem is well-fixed with 15 degrees of anteversion. What is the most appropriate surgical management?

. Closed reduction and hip spica cast
. Revision of the acetabular component to increase anteversion
. Exchange of the modular head to a longer neck length
. Placement of a constrained acetabular liner into the current shell
. Revision of the femoral stem to increase anteversion

Correct Answer & Explanation

. Revision of the acetabular component to increase anteversion


Explanation

The combined anteversion (cup + stem) in this patient is 20 degrees, which is low and predisposes to posterior instability. The normal safe zone for the acetabular component is typically 15-20 degrees of anteversion. Since the cup is retroverted/under-anteverted (5 degrees), revising the cup to increase anteversion is the most appropriate biomechanical solution. Constrained liners are generally reserved for abductor deficiency, massive soft tissue compromise, or cognitive impairment when the components are already optimally positioned.

Question 3775

Topic: 3. Adult Reconstruction (Hip & Knee)

A 58-year-old woman with a metal-on-metal total hip arthroplasty presents with progressive groin pain. Laboratory tests show significantly elevated serum cobalt and chromium levels. A metal artifact reduction sequence (MARS) MRI shows a thick-walled cystic mass communicating with the hip joint space causing displacement of the surrounding soft tissues. What is the most appropriate management?

. CT-guided percutaneous aspiration of the mass
. Revision to a metal-on-polyethylene bearing surface
. Oral antibiotics and observation
. Isolated open irrigation and debridement of the mass
. Revision of the femoral stem only

Correct Answer & Explanation

. Revision to a metal-on-polyethylene bearing surface


Explanation

Adverse local tissue reaction (ALTR) or pseudotumor is a severe complication of metal-on-metal THAs, often driven by edge loading, trunnionosis, or metal wear debris. Management of a symptomatic ALTR with elevated metal ions and progressive soft-tissue destruction requires revision of the bearing surfaces to a non-metal-on-metal construct (e.g., metal-on-polyethylene or ceramic-on-polyethylene) along with thorough debridement of the pseudotumor.

Question 3776

Topic: 3. Adult Reconstruction (Hip & Knee)

A 72-year-old man with a well-functioning right total hip arthroplasty placed 8 years ago presents with 3 days of acute, severe right hip pain and an inability to bear weight. He reports having a tooth extracted for a severe dental abscess 2 weeks ago. Hip aspiration yields synovial fluid with 65,000 WBC/uL and 95% polymorphonuclear cells. Radiographs show stable components with no radiolucencies. What is the most appropriate surgical management?

. One-stage revision arthroplasty
. Two-stage revision arthroplasty with an antibiotic spacer
. Irrigation and debridement with modular polyethylene exchange
. Resection arthroplasty (Girdlestone procedure)
. Long-term chronic suppressive intravenous antibiotics

Correct Answer & Explanation

. Irrigation and debridement with modular polyethylene exchange


Explanation

This patient presents with an acute hematogenous periprosthetic joint infection (symptoms lasting less than 3 weeks in a previously well-functioning, stable arthroplasty). The standard of care for acute hematogenous PJI with radiographically well-fixed implants is irrigation and debridement with modular component (polyethylene) exchange, often referred to as DAIR (Debridement, Antibiotics, and Implant Retention), followed by targeted systemic antibiotics.

Question 3777

Topic: 3. Adult Reconstruction (Hip & Knee)

A 78-year-old woman sustains a ground-level fall and presents with severe right thigh pain.

Radiographs show a periprosthetic fracture around her femoral stem. There is clear evidence of stem subsidence and a wide radiolucent line at the cement-bone interface, indicating aseptic loosening prior to the fall. The fracture extends to just distal to the tip of the stem, but there is adequate cortical bone stock distally. According to the Vancouver classification, what is the most appropriate treatment?

. Open reduction and internal fixation with a lateral locking plate and cables
. Open reduction and internal fixation with cerclage cables only
. Revision to a long cementless fully porous-coated or fluted tapered stem
. Revision using a standard length cemented stem
. Nonoperative management with a hinged fracture brace and protected weight-bearing

Correct Answer & Explanation

. Revision to a long cementless fully porous-coated or fluted tapered stem


Explanation

This scenario describes a Vancouver B2 periprosthetic femur fracture (a fracture around the stem, with a loose stem, but with good bone stock). The gold standard treatment for a Vancouver B2 fracture is revision of the loose femoral component using a long cementless stem (such as an extensively porous-coated or fluted tapered modular stem) to achieve diaphyseal fixation bypassing the fracture site, usually supplemented with cables for the fracture.

Question 3778

Topic: 3. Adult Reconstruction (Hip & Knee)

A 64-year-old man presents with a 6-month history of progressive right hip pain 5 years after receiving a cementless total hip arthroplasty with a 36-mm cobalt-chromium head on a titanium stem. Radiographs show well-fixed components with no evidence of osteolysis. Laboratory evaluation reveals a markedly elevated serum cobalt level with a normal serum chromium level. Hip aspiration is negative for infection. What is the most likely cause of this patient's symptoms?

. Polyethylene wear debris
. Aseptic loosening of the acetabular component
. Mechanically assisted crevice corrosion at the head-neck junction
. Unrecognized indolent periprosthetic joint infection
. Impingement of the iliopsoas tendon

Correct Answer & Explanation

. Mechanically assisted crevice corrosion at the head-neck junction


Explanation

An elevated serum cobalt level that is disproportionately higher than the chromium level in a patient with a metal head on a titanium stem is the hallmark of mechanically assisted crevice corrosion (MACC), or trunnionosis, at the modular head-neck taper junction. This phenomenon is often associated with large diameter metal heads, which increase the frictional torque at the trunnion.

Question 3779

Topic: 3. Adult Reconstruction (Hip & Knee)

A 52-year-old highly active man underwent a total hip arthroplasty with a ceramic-on-ceramic bearing surface 3 years ago. He is highly satisfied with his hip function but complains of a loud, audible "squeaking" noise when bending, walking, or rising from a chair. Which of the following component positions or surgical factors is most strongly associated with this phenomenon?

. Acetabular component retroversion
. Increased femoral stem offset
. Acetabular component placed in excessive abduction
. A femoral stem placed in valgus alignment
. Use of a small diameter femoral head

Correct Answer & Explanation

. Acetabular component placed in excessive abduction


Explanation

Squeaking is a specific complication of ceramic-on-ceramic total hip arthroplasty, reported in a subset of patients. It is most strongly associated with edge loading caused by component malposition, specifically acetabular components placed in excessive abduction or anteversion. This leads to loss of fluid film lubrication, micro-separation, and stripe wear on the ceramic, which generates the audible squeaking sound.

Question 3780

Topic: 3. Adult Reconstruction (Hip & Knee)

A 38-year-old male is involved in a high-speed motor vehicle collision.

Radiographs demonstrate a completely displaced, intracapsular femoral neck fracture (Garden IV). He has no significant past medical history and is highly active. What is the most appropriate initial surgical management?

. Total hip arthroplasty
. Bipolar hemiarthroplasty
. Unipolar hemiarthroplasty
. Closed reduction and percutaneous pinning with three parallel cancellous screws
. Open reduction and internal fixation with a sliding hip screw and derotation screw

Correct Answer & Explanation

. Open reduction and internal fixation with a sliding hip screw and derotation screw


Explanation

In young, physiologically active patients (typically < 60 years old) with displaced femoral neck fractures, head-preserving surgery with urgent open reduction and internal fixation (ORIF) is indicated to preserve the native hip joint, despite the high risk of avascular necrosis. Due to the high shear forces inherent in vertical or completely displaced fractures in young adults, a sliding hip screw (often supplemented with a derotation screw) or a length-stable construct provides superior biomechanical stability compared to multiple cancellous screws alone.