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Question 2621

Topic: 3. Adult Reconstruction (Hip & Knee)

A 55-year-old male undergoes a total hip arthroplasty utilizing a ceramic-on-ceramic bearing surface. One year later, he complains of a highly audible 'squeaking' noise when walking. Which of the following factors is most strongly associated with this phenomenon?

. Acetabular cup retroversion leading to edge loading
. Excessive femoral offset
. Use of a smaller diameter femoral head (e.g., 28 mm)
. Acetabular component anteversion greater than 20 degrees
. Impugnment of the psoas tendon against the anterior acetabular rim

Correct Answer & Explanation

. Acetabular cup retroversion leading to edge loading


Explanation

Squeaking in ceramic-on-ceramic THA is a recognized complication and is most strongly associated with edge loading. Edge loading occurs due to component malpositioning, particularly acetabular cup retroversion, excessive anteversion, or steep inclination (abduction angle). This causes stripe wear and loss of fluid-film lubrication, resulting in the characteristic squeak.

Question 2622

Topic: 3. Adult Reconstruction (Hip & Knee)

In total hip arthroplasty, the use of highly cross-linked polyethylene (HXLPE) has significantly reduced wear rates compared to conventional polyethylene. Which of the following mechanical properties is most likely decreased as a direct result of the high-dose irradiation process used to create HXLPE?

. Fatigue strength
. Wear resistance
. Oxidation resistance
. Adhesive wear
. Melting point

Correct Answer & Explanation

. Fatigue strength


Explanation

The process of highly cross-linking polyethylene through high-dose irradiation significantly improves wear resistance but compromises its mechanical properties, resulting in a decrease in fatigue strength, yield strength, and ultimate tensile strength. Free radicals generated during irradiation must be quenched (e.g., via remelting or annealing) to prevent oxidation.

Question 2623

Topic: 3. Adult Reconstruction (Hip & Knee)

A 68-year-old female presents with an audible and palpable 'clunk' in her knee 9 months after a posterior-stabilized total knee arthroplasty. The clunk occurs as the knee actively extends from 45 degrees of flexion. What is the most likely pathophysiologic cause of this phenomenon?

. Asymmetric wear of the polyethylene insert
. Impingement of a fibrotic nodule on the undersurface of the quadriceps tendon against the intercondylar box
. Subluxation of the patella over the lateral femoral condyle
. Loosening of the tibial baseplate
. Avulsion of the popliteus tendon

Correct Answer & Explanation

. Impingement of a fibrotic nodule on the undersurface of the quadriceps tendon against the intercondylar box


Explanation

Patellar clunk syndrome is a complication unique to posterior-stabilized TKA. It is caused by the formation of a fibrotic nodule on the undersurface of the distal quadriceps tendon. During knee flexion, the nodule falls into the intercondylar box of the femoral component. As the knee actively extends, the nodule catches on the superior edge of the box and 'clunks' as it snaps out.

Question 2624

Topic: 3. Adult Reconstruction (Hip & Knee)
Macrophage-induced osteolysis is a primary cause of aseptic loosening in total joint arthroplasty. Which of the following specific wear particles is considered the most biologically active in stimulating the macrophage response leading to osteolysis?
. Polymethylmethacrylate (PMMA) particles measuring 10-50 micrometers
. Titanium alloy particles measuring 5-10 micrometers
. Cobalt-chromium particles measuring less than 0.1 micrometers
. Ultra-high molecular weight polyethylene (UHMWPE) particles measuring 0.1-1.0 micrometers
. Ceramic particles measuring 1-5 micrometers

Correct Answer & Explanation

. Ultra-high molecular weight polyethylene (UHMWPE) particles measuring 0.1-1.0 micrometers


Explanation

The size and volume of wear particles dictate their biological activity. Macrophages preferentially phagocytose particles in the submicron range (0.1 to 1.0 micrometers). UHMWPE particles within this specific size range are the most numerous and most biologically active culprits in stimulating macrophages to release pro-inflammatory cytokines, ultimately leading to osteoclast activation and osteolysis.

Question 2625

Topic: 3. Adult Reconstruction (Hip & Knee)

A 65-year-old woman undergoes total hip arthroplasty using a highly cross-linked polyethylene liner. What is the primary negative biomechanical consequence of increasing the radiation dose during the cross-linking process of the polyethylene?

. Increased volumetric wear
. Decreased oxidation resistance
. Decreased fatigue strength and fracture toughness
. Increased coefficient of friction
. Decreased ultimate tensile strength of the femoral stem

Correct Answer & Explanation

. Decreased fatigue strength and fracture toughness


Explanation

Highly cross-linked polyethylene (HXLPE) is manufactured by irradiating the material, which creates cross-links that significantly reduce volumetric wear. However, this process decreases the material's mechanical properties, specifically reducing its fatigue strength, ductility, and fracture toughness, making it more susceptible to rim fractures.

Question 2626

Topic: 3. Adult Reconstruction (Hip & Knee)

When diagnosing a periprosthetic joint infection (PJI), clinicians often rely on the Musculoskeletal Infection Society (MSIS) criteria. Which of the following findings is considered one of the 'major' criteria, which by itself is definitively diagnostic for a PJI?

. Elevated synovial fluid alpha-defensin level
. A sinus tract communicating directly with the prosthesis
. Purulent fluid noted in the affected joint during aspiration
. Elevated serum ESR (>30 mm/hr) and CRP (>10 mg/L)
. Greater than 5 neutrophils per high-power field in 5 distinct fields at 400x magnification

Correct Answer & Explanation

. A sinus tract communicating directly with the prosthesis


Explanation

According to the internationally recognized MSIS criteria for PJI, there are two 'major' criteria: 1) A sinus tract communicating with the prosthesis, and 2) Two positive periprosthetic cultures with phenotypically identical organisms. The presence of either definitively diagnoses a PJI. The other options are minor criteria.

Question 2627

Topic: 3. Adult Reconstruction (Hip & Knee)

Which of the following defines the "safe zone" for acetabular component positioning in total hip arthroplasty as classically described by Lewinnek?

. 40 +/- 10 degrees of abduction and 15 +/- 10 degrees of anteversion
. 45 +/- 10 degrees of abduction and 20 +/- 10 degrees of anteversion
. 30 +/- 10 degrees of abduction and 15 +/- 10 degrees of anteversion
. 40 +/- 10 degrees of abduction and 25 +/- 10 degrees of anteversion
. 50 +/- 10 degrees of abduction and 10 +/- 10 degrees of anteversion

Correct Answer & Explanation

. 40 +/- 10 degrees of abduction and 15 +/- 10 degrees of anteversion


Explanation

Lewinnek classically described the safe zone for acetabular cup placement as 40 +/- 10 degrees of abduction (inclination) and 15 +/- 10 degrees of anteversion to minimize the risk of dislocation.

Question 2628

Topic: 3. Adult Reconstruction (Hip & Knee)

During a total knee arthroplasty, after making the initial bone cuts and inserting trial components, the surgeon notes that the knee is symmetric and stable in extension, but tight symmetrically in flexion. What is the most appropriate corrective step?

. Resect more distal femur
. Downsize the femoral component
. Increase the tibial slope
. Resect more proximal tibia
. Release the posterior capsule

Correct Answer & Explanation

. Downsize the femoral component


Explanation

A knee that is symmetric and stable in extension but symmetrically tight in flexion indicates an isolated tight flexion gap. The most appropriate and direct step is to decrease the anteroposterior (AP) dimension of the femoral component by downsizing it, which increases the flexion gap without altering the extension gap.

Question 2629

Topic: 3. Adult Reconstruction (Hip & Knee)

In total hip arthroplasty, the use of highly cross-linked polyethylene (HXLPE) significantly reduces volumetric wear. However, the radiation cross-linking and subsequent thermal treatment processes result in which of the following biomechanical trade-offs?

. Decreased fatigue crack propagation resistance and yield strength.
. Increased elastic modulus leading to stress shielding.
. Increased yield strength but decreased ultimate tensile strength.
. Decreased oxidation resistance due to the elimination of free radicals.
. Increased ultimate tensile strength and ductility.

Correct Answer & Explanation

. Decreased fatigue crack propagation resistance and yield strength.


Explanation

While high-dose irradiation increases cross-linking (improving wear resistance), it generates free radicals that can cause oxidation. To eliminate free radicals, thermal treatments (melting or annealing) are used. However, this process decreases the crystallinity of the polyethylene, resulting in decreased mechanical properties, specifically decreased yield strength, ultimate tensile strength, and fatigue crack propagation resistance.

Question 2630

Topic: 3. Adult Reconstruction (Hip & Knee)

During a cruciate-retaining total knee arthroplasty, the trial reduction reveals that the knee is well-balanced and symmetric in full extension but is excessively tight in 90 degrees of flexion. Which of the following surgical modifications is most appropriate to balance the knee?

. Resect more bone from the distal femur.
. Downsize the femoral component using a posterior referencing system.
. Increase the posterior slope of the proximal tibial cut.
. Release the superficial medial collateral ligament.
. Upsize the femoral component.

Correct Answer & Explanation

. Increase the posterior slope of the proximal tibial cut.


Explanation

A knee that is tight in flexion but balanced in extension has an isolated tight flexion gap. Increasing the posterior slope of the tibial cut selectively increases the flexion gap without significantly affecting the extension gap. Alternatively, anteriorizing the femoral component or using a smaller femoral component (depending on the referencing system) could help, but increasing the tibial slope is a direct, classic solution.

Question 2631

Topic: 3. Adult Reconstruction (Hip & Knee)

During a posterior-stabilized total knee arthroplasty (TKA), the surgeon observes excessive femoral rollback resulting in severe posterior impingement of the tibial post against the femoral cam during deep flexion. Which of the following technical errors is the most likely cause of this kinematic abnormality?

. The femoral component is undersized and placed in excessive flexion.
. The tibial slope is excessive (too much posterior slope).
. The joint line is elevated significantly.
. The femoral component is internally rotated.
. The popliteus tendon was completely excised.

Correct Answer & Explanation

. The tibial slope is excessive (too much posterior slope).


Explanation

In a posterior-stabilized TKA, introducing excessive posterior slope to the tibial component effectively translates the tibial post anteriorly relative to the femur. This causes early engagement of the femoral cam against the tibial post during flexion, leading to excessive rollback, premature wear, posterior impingement, and in severe cases, anterior subluxation of the femur or post fracture.

Question 2632

Topic: 3. Adult Reconstruction (Hip & Knee)

Which of the following factors is most strongly associated with the phenomenon of 'squeaking' following a Ceramic-on-Ceramic total hip arthroplasty?

. The use of a large-diameter femoral head (>36mm)
. Decreased body mass index (BMI)
. Acetabular cup malposition leading to edge loading
. Subclinical periprosthetic joint infection
. Use of a titanium rather than cobalt-chrome femoral stem

Correct Answer & Explanation

. Acetabular cup malposition leading to edge loading


Explanation

Squeaking is a known complication specific to hard-on-hard bearings, particularly Ceramic-on-Ceramic THA. The most significant mechanical factor associated with squeaking is edge loading, which typically results from acetabular component malposition (e.g., excessive inclination or excessive version). This disruption of fluid film lubrication causes localized stripe wear and generates the acoustic squeaking phenomenon.

Question 2633

Topic: 3. Adult Reconstruction (Hip & Knee)

During the trial reduction phase of a posterior-stabilized total knee arthroplasty, the surgeon notes that the knee is exceptionally tight in flexion (difficulty reaching 90 degrees), but it is stable, fully extended, and well-balanced in extension. Which of the following is the most appropriate surgical adjustment?

. Resect additional bone from the distal femur
. Decrease the AP size of the femoral component
. Downsize the thickness of the tibial polyethylene insert
. Release the posterior capsule
. Resect additional bone from the proximal tibia

Correct Answer & Explanation

. Decrease the AP size of the femoral component


Explanation

A knee that is tight in flexion but balanced in extension indicates an isolated tight flexion gap. To increase the flexion gap without altering the extension gap, the surgeon should decrease the anteroposterior (AP) size of the femoral component (often requiring anterior referencing to avoid notching and shifting the posterior condyles anteriorly). Resecting more proximal tibia or downsizing the poly would loosen both flexion and extension gaps equally. Resecting distal femur only affects the extension gap.

Question 2634

Topic: 3. Adult Reconstruction (Hip & Knee)

During the trialing phase of a posterior-stabilized total knee arthroplasty, the knee is found to be symmetrically tight in flexion but well-balanced and stable in extension. Which of the following is the most appropriate next surgical step to balance the knee?

. Resect an additional 2 mm from the distal femur
. Resect an additional 2 mm from the proximal tibia
. Downsize the femoral component
. Upsize the femoral component
. Release the posterior capsule

Correct Answer & Explanation

. Downsize the femoral component


Explanation

If the knee is tight in flexion but balanced in extension, the flexion gap needs to be increased without altering the extension gap. Downsizing the femoral component achieves this by reducing the anteroposterior dimension of the femur (translating the posterior condyles anteriorly) without changing the distal femoral cut, thereby opening the flexion gap.

Question 2635

Topic: 3. Adult Reconstruction (Hip & Knee)

When performing a cemented total hip arthroplasty using a collarless, polished, taper-slip femoral stem (e.g., the Exeter stem), which of the following biomechanical principles describes the primary mechanism by which the stem achieves long-term stability within the cement mantle?

. Proximal stress shielding to stimulate bone ingrowth
. Cortical bypass leading to distal load transfer
. Endosteal cancellous interdigitation with the polished stem
. Slight subsidence causing radial compression (hoop stresses) of the cement
. Rigid locking to prevent any axial micro-motion

Correct Answer & Explanation

. Slight subsidence causing radial compression (hoop stresses) of the cement


Explanation

Collarless, polished, taper-slip stems are specifically designed to act as a wedge. They are meant to subside slightly within the cement mantle under axial load. Because the stem is tapered and highly polished (preventing bonding to the cement), this controlled subsidence generates outward radial forces that compress the cement mantle (creating hoop stresses), which tightly locks the cement against the surrounding bone.

Question 2636

Topic: Total Hip Arthroplasty (THA)

A 65-year-old female presents with groin pain and swelling three years after undergoing a primary total hip arthroplasty utilizing a metal head on a highly cross-linked polyethylene liner with a titanium femoral stem. Metal ion analysis and MRI are suggestive of trunnionosis (mechanically assisted crevice corrosion). Which of the following serum metal ion profiles is most characteristic of this specific complication?

. Significantly elevated Titanium with normal Cobalt and Chromium
. Markedly elevated Chromium with normal Cobalt
. Elevated Cobalt disproportionately higher than Chromium
. Elevated Chromium disproportionately higher than Cobalt
. Elevated Vanadium and Aluminum with normal Cobalt and Chromium

Correct Answer & Explanation

. Elevated Cobalt disproportionately higher than Chromium


Explanation

Trunnionosis, or mechanically assisted crevice corrosion at the head-neck junction of a total hip arthroplasty, typically involves a cobalt-chromium (CoCr) head on a titanium (Ti) alloy stem. Corrosion at this modular junction leads to the preferential release of cobalt ions. Consequently, patients with trunnionosis characteristically present with an elevated serum cobalt-to-chromium ratio (Co > Cr), distinguishing it from wear at a metal-on-metal articular surface where Co and Cr are typically elevated more equally.

Question 2637

Topic: 3. Adult Reconstruction (Hip & Knee)

A 68-year-old male is evaluated for isolated anterior knee pain with a palpable 'catching' sensation when extending his knee from a flexed position. He underwent a posterior-stabilized total knee arthroplasty 18 months ago. Examination reveals a painful snap at approximately 30 to 40 degrees of knee flexion during active extension. What is the most definitive and appropriate treatment for this condition?

. Open patellar component revision to a thinner button
. Arthroscopic excision of a fibrous nodule at the superior pole of the patella
. Revision of the femoral component to a cruciate-retaining design
. Manipulation under anesthesia followed by aggressive physical therapy
. Tibial tubercle osteotomy for extensor mechanism realignment

Correct Answer & Explanation

. Arthroscopic excision of a fibrous nodule at the superior pole of the patella


Explanation

The patient's presentation is classic for 'patellar clunk syndrome,' a complication most commonly associated with posterior-stabilized total knee arthroplasty designs. It is caused by the formation of a fibrous nodule at the superior pole of the patella or distal quadriceps tendon. During knee extension, this nodule catches in the intercondylar box of the femoral component, producing a painful clunk. The definitive and highly successful treatment is arthroscopic debridement/excision of the fibrous nodule.

Question 2638

Topic: 3. Adult Reconstruction (Hip & Knee)

During trialing in a primary total knee arthroplasty, the knee is found to be well-balanced and symmetric in full extension, but the flexion gap is unacceptably tight. Which of the following maneuvers is the most appropriate next step to balance the knee?

. Resect more distal femur
. Downsize the femoral component
. Release the posterior cruciate ligament
. Recut the proximal tibia with less posterior slope
. Upsize the tibial polyethylene liner

Correct Answer & Explanation

. Downsize the femoral component


Explanation

A knee that is balanced in extension but tight in flexion requires an increase in the flexion gap without altering the extension gap. Downsizing the femoral component (with anterior referencing) resects more posterior femoral condylar bone, opening the flexion gap. Increasing posterior tibial slope would also work, but decreasing it would make flexion tighter.

Question 2639

Topic: 3. Adult Reconstruction (Hip & Knee)

The introduction of highly cross-linked polyethylene (HXLPE) in total hip arthroplasty has significantly reduced volumetric wear rates. However, the radiation cross-linking process detrimentally affects which of the following material properties?

. Fatigue crack propagation resistance and ultimate tensile strength
. Oxidation resistance when followed by remelting
. Elastic modulus
. Biocompatibility
. Hydrophilicity

Correct Answer & Explanation

. Fatigue crack propagation resistance and ultimate tensile strength


Explanation

While high doses of gamma radiation induce cross-linking that improves wear resistance, it compromises mechanical properties such as ductility, fatigue crack propagation resistance, and ultimate tensile strength. This makes the material more susceptible to fracture, particularly in thin sections or constrained designs.

Question 2640

Topic: 3. Adult Reconstruction (Hip & Knee)

During a posterior-stabilized total knee arthroplasty, using a measured resection technique, the surgeon assesses the gaps with trial components. The knee is symmetric and perfectly balanced in extension, but it is symmetrically tight in flexion. What is the most appropriate next step to balance the knee without altering the extension gap?

. Recut the distal femur to take more bone
. Release the posterior cruciate ligament
. Downsize the femoral component
. Upsize the tibial polyethylene insert
. Release the medial collateral ligament

Correct Answer & Explanation

. Downsize the femoral component


Explanation

If the extension gap is perfectly balanced but the flexion gap is tight, the surgeon must increase the flexion gap without affecting the extension gap. In anterior referencing systems, downsizing the femoral component reduces the posterior femoral condylar offset, thereby opening the flexion gap without changing the distal femoral cut (which controls the extension gap).