This practice set contains high-yield board review questions covering key concepts in Physiology & Rehabilitation. Each clinical scenario is designed to test your diagnostic and management skills relevant to this subspecialty.
Question 341
Topic: Physiology & Rehabilitation
Which of the following is considered a hallmark clinical feature differentiating an intramedullary spinal tumor from an extradural tumor?
Correct Answer & Explanation
. Early dissociated sensory loss (loss of pain/temp with preserved touch/proprioception)
Explanation
Early dissociated sensory loss (syringomyelic pattern), where pain and temperature sensation are lost while touch and proprioception are preserved, is a hallmark feature of intramedullary lesions, especially those causing a syrinx or affecting the spinothalamic tracts crossing in the central cord. This is due to disruption of the decussating spinothalamic fibers. While other symptoms like motor weakness, pain, and bladder dysfunction can occur with any spinal tumor, this specific sensory pattern points strongly to an intramedullary pathology.
Question 342
Topic: Physiology & Rehabilitation
A 50-year-old patient presents with lateral epicondylitis. An occupational therapist recommends an eccentric exercise program. What is the primary theoretical benefit of eccentric exercises in tendinopathy rehabilitation?
Correct Answer & Explanation
. To induce collagen remodeling and strengthen the tendon.
Explanation
The primary theoretical benefit of eccentric exercises in tendinopathy rehabilitation is to induce collagen remodeling, strengthen the tendon, and improve its load-bearing capacity. While they may contribute to flexibility and improved performance (by strengthening the entire muscle-tendon unit), the specific effect on tendon structure and resistance to injury is the key. They do not directly reduce inflammation, and proprioception is a secondary benefit. The progressive loading during the lengthening phase of muscle contraction is thought to stimulate fibroblast activity and collagen synthesis in a more organized fashion.
Question 343
Topic: Physiology & Rehabilitation
In a patient with chronic lateral ankle instability, what is the 'star excursion balance test' primarily used to assess?
Correct Answer & Explanation
. Dynamic balance, proprioception, and neuromuscular control.
Explanation
The Star Excursion Balance Test (SEBT) is a commonly used clinical assessment tool for dynamic balance, proprioception, and neuromuscular control of the lower extremity. It requires the patient to maintain balance on one leg while reaching with the contralateral leg in various directions, thereby challenging the ankle's stability in a functional manner. It does not directly measure static balance, muscle strength, ligamentous laxity, or pain levels, though it can be influenced by these factors.
Question 344
Topic: Physiology & Rehabilitation
Which of the following types of ankle instability is characterized by a feeling of 'giving way' without objective evidence of ligamentous laxity on examination or stress radiographs?
Correct Answer & Explanation
. Functional instability
Explanation
Functional instability describes the subjective sensation of the ankle 'giving way' or feeling unstable, without demonstrable objective laxity (e.g., on stress radiographs). This is often attributed to impaired proprioception and neuromuscular control deficits. Mechanical instability, on the other hand, involves objective ligamentous laxity. Chronic instability refers to persistent symptoms, which can be either mechanical, functional, or both.
Question 345
Topic: Physiology & Rehabilitation
What aspect of chronic lateral ankle instability is most effectively addressed by a comprehensive physiotherapy program, even if mechanical laxity persists?
Correct Answer & Explanation
. Improvement of functional stability through enhanced proprioception and neuromuscular control.
Explanation
A comprehensive physiotherapy program is highly effective in improving functional stability, even when some degree of mechanical laxity persists. This is achieved by enhancing proprioception, strengthening dynamic stabilizers (peroneals), and improving neuromuscular control. Physiotherapy cannot directly restore torn ligaments, correct structural deformities like cavovarus foot, or directly repair OCLs. While it aims to reduce pain and swelling, complete elimination is not always possible without addressing underlying mechanical issues or other pathologies.
Question 346
Topic: Physiology & Rehabilitation
The 'red-red zone' of the meniscus refers to the region that is:
Correct Answer & Explanation
. Vascularized and capable of intrinsic healing.
Explanation
The 'red-red zone' is the outermost peripheral region of the meniscus (approximately 10-30% of its width) that receives a direct blood supply from the perimeniscal capillary plexus. Tears in this zone have the best potential for biological healing due to the presence of blood-borne healing factors and cells.
Question 347
Topic: Physiology & Rehabilitation
Which aspect of meniscal function is most impaired by a total meniscectomy?
Correct Answer & Explanation
. Load distribution and shock absorption.
Explanation
A total meniscectomy profoundly impairs the meniscus's primary biomechanical functions: load distribution and shock absorption. By removing the menisci, the contact area between the femoral and tibial condyles is significantly reduced, leading to a marked increase in peak contact stresses and accelerated articular cartilage degeneration. While proprioception and lubrication also suffer, the load-bearing deficit is the most critical factor for long-term joint health.
Question 348
Topic: Physiology & Rehabilitation
The presence of sensory nerve endings (mechanoreceptors and nociceptors) in the menisci suggests their role in:
Correct Answer & Explanation
. Proprioception and pain perception.
Explanation
The menisci are innervated, particularly in their peripheral vascularized zones and horn attachments, by both mechanoreceptors (e.g., Ruffini endings, Pacinian corpuscles, Golgi tendon organ-like endings) and free nerve endings (nociceptors). This innervation indicates their crucial role in providing proprioceptive feedback (sense of joint position and movement) to the central nervous system and in mediating pain perception.
Question 349
Topic: Physiology & Rehabilitation
During an eccentric muscle contraction, which of the following statements best describes the physiological mechanics occurring within the sarcomere?
Correct Answer & Explanation
. The muscle generates force while actin filaments are pulled away from the center of the sarcomere.
Explanation
In an eccentric contraction, the muscle lengthens while generating force. The actin filaments are pulled away from the center of the sarcomere (M-line) by external forces that exceed the force generated by the cross-bridges. The A-band remains constant in length, while the I-band lengthens.
Question 350
Topic: Physiology & Rehabilitation
During rehabilitation, patients perform various types of muscle contractions. Which type of contraction generates the highest maximum force and is most commonly associated with delayed onset muscle soreness (DOMS)?
Correct Answer & Explanation
. Eccentric
Explanation
Eccentric contractions occur when a muscle lengthens while under tension. They can generate the highest forces of any contraction type but are also most highly correlated with microtrauma and subsequent delayed onset muscle soreness.
Question 351
Topic: Physiology & Rehabilitation
During the normal human gait cycle, which muscle group undergoes a critical eccentric contraction during the initial contact to the loading response phase to control joint motion and absorb shock?
Correct Answer & Explanation
. Quadriceps
Explanation
From initial contact (heel strike) to the loading response, the knee flexes slightly to absorb the shock of body weight. The quadriceps muscle group contracts eccentrically during this brief period to control the rate and extent of knee flexion, thereby stabilizing the limb as weight is accepted.
Question 352
Topic: Physiology & Rehabilitation
Postural muscles, such as the soleus, are uniquely adapted to resist fatigue during prolonged standing. Which of the following profiles best describes the predominant muscle fiber type found in the soleus?
Correct Answer & Explanation
. Slow twitch, aerobic, high mitochondrial density
Explanation
The soleus is primarily composed of Type I muscle fibers. Type I fibers are slow-twitch, highly oxidative (aerobic), rich in myoglobin and mitochondria, and highly resistant to fatigue.
Question 353
Topic: Physiology & Rehabilitation
Type I (slow-twitch) skeletal muscle fibers are specialized for endurance activities. Compared to Type IIb fibers, Type I fibers possess which of the following characteristics?
Correct Answer & Explanation
. Higher mitochondrial density
Explanation
Type I muscle fibers are optimized for aerobic metabolism and fatigue resistance. They have a higher mitochondrial density, higher myoglobin content, greater capillary density, and rely primarily on oxidative phosphorylation.
Question 354
Topic: Physiology & Rehabilitation
During the normal human gait cycle, the peak joint reaction force at the hip occurs during which specific phase?
Correct Answer & Explanation
. Terminal stance
Explanation
The peak joint reaction force at the hip reaches approximately 2.5 to 3 times body weight and occurs during the terminal stance phase. This peak is driven primarily by the contraction of the hip abductor muscles to stabilize the pelvis prior to toe-off.
Question 355
Topic: Physiology & Rehabilitation
During a rehabilitation exercise protocol for a patient recovering from a patellar tendon repair, the physical therapist instructs the patient to slowly lower a weight from full knee extension to 90 degrees of flexion. In this phase, the quadriceps muscle is actively generating force while simultaneously lengthening. This type of muscle contraction is defined as:
Correct Answer & Explanation
. Eccentric
Explanation
An eccentric contraction occurs when the muscle lengthens while under tension (generating force). A concentric contraction occurs when the muscle shortens while generating force. An isometric contraction occurs when tension is generated without a change in muscle length. Isokinetic refers to contraction at a constant speed, and isotonic refers to contraction against a constant load.
Question 356
Topic: Physiology & Rehabilitation
During a rehabilitation protocol following a major orthopedic surgery, a physical therapist emphasizes eccentric muscle contractions. Which of the following statements best describes an eccentric contraction?
Correct Answer & Explanation
. The muscle lengthens while generating force
Explanation
An eccentric contraction occurs when a muscle generates force while actively lengthening. This often occurs during deceleration activities (e.g., the quadriceps during the downward phase of a squat). Eccentric contractions can generate the highest forces and are most associated with delayed onset muscle soreness (DOMS).
Question 357
Topic: Physiology & Rehabilitation
Delayed onset muscle soreness (DOMS) following intensive physical activity is most strongly associated with which type of muscle contraction?
Correct Answer & Explanation
. Eccentric
Explanation
Delayed onset muscle soreness (DOMS) is primarily caused by eccentric muscle contractions, where the muscle lengthens while under active tension. This mechanical stress leads to microtrauma of the muscle fibers and a subsequent inflammatory response.
Question 358
Topic: Physiology & Rehabilitation
Skeletal muscle contractions are classified by how the muscle changes length under tension. Which type of contraction generates the highest amount of force and is most commonly associated with delayed onset muscle soreness (DOMS)?
Correct Answer & Explanation
. Eccentric contraction
Explanation
Eccentric contractions occur when the muscle lengthens while under tension, and they can generate greater force than concentric or isometric contractions. They are the primary cause of muscle microtrauma leading to delayed onset muscle soreness (DOMS).
Question 359
Topic: Physiology & Rehabilitation
Following a traumatic nerve transection, skeletal muscle undergoes characteristic physiologic changes. Which of the following is a classic finding in denervated skeletal muscle at 3-4 weeks post-injury?
Correct Answer & Explanation
. Upregulation of extrajunctional acetylcholine receptors
Explanation
Following denervation, skeletal muscle becomes hypersensitive to acetylcholine due to the massive upregulation and spread of extrajunctional acetylcholine receptors across the entire sarcolemma. This manifests as spontaneous fibrillation potentials on EMG.
Question 360
Topic: Physiology & Rehabilitation
During a normal human gait cycle, at what specific phase does the tibialis anterior exhibit its peak electromyographic (EMG) activity?
Correct Answer & Explanation
. Initial contact (heel strike) to loading response
Explanation
The tibialis anterior peaks in activity during the transition from initial contact to the loading response. It fires eccentrically during this phase to control ankle plantar flexion and prevent 'foot slap'.
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