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Question 1721

Topic: Biomechanics & Biomaterials

Ligaments and tendons possess viscoelastic properties that affect their biomechanical behavior under load. The biomechanical phenomenon where the internal stress within a tissue progressively decreases over time while it is held at a constant length (strain) is defined as:

. Creep
. Stress relaxation
. Hysteresis
. Isotropy
. Fatigue failure

Correct Answer & Explanation

. Stress relaxation


Explanation

Stress relaxation refers to the gradual decrease in internal tissue stress when it is held at a fixed constant strain (length). In contrast, creep is the progressive elongation (deformation) of a material over time when subjected to a constant load (stress).

Question 1722

Topic: Biomechanics & Biomaterials

An orthopedic surgeon revises a failed femoral neck fracture fixation by substituting a stainless steel side plate with a titanium plate, but leaves the original stainless steel lag screw in place. Several months later, rapid implant failure occurs with surrounding metallic debris. This phenomenon is primarily an example of:

. Fretting corrosion
. Galvanic corrosion
. Crevice corrosion
. Pitting corrosion
. Intergranular corrosion

Correct Answer & Explanation

. Galvanic corrosion


Explanation

Galvanic corrosion occurs when two electrochemically dissimilar metals (e.g., titanium and stainless steel) are in direct contact within a conductive fluid environment (body fluids). This creates an electrochemical cell leading to accelerated degradation of the less noble metal.

Question 1723

Topic: Biomechanics & Biomaterials

Bone provides profound structural support primarily due to its dense inorganic matrix. Which of the following represents the predominant mature inorganic mineral constituent of healthy human cortical bone?

. Calcium carbonate
. Calcium pyrophosphate dihydrate
. Calcium hydroxyapatite
. Monosodium urate monohydrate
. Calcium oxalate

Correct Answer & Explanation

. Calcium hydroxyapatite


Explanation

Approximately 60-65% of bone by weight is composed of inorganic mineral salts. The vast majority of this mineral is present in the form of calcium hydroxyapatite [Ca10(PO4)6(OH)2], which provides the bone with its high compressive strength.

Question 1724

Topic: Biomechanics & Biomaterials
Increasing the radiation dose during the cross-linking process of ultra-high molecular weight polyethylene (UHMWPE) for total hip arthroplasty has which of the following biomechanical effects?
. Increases fatigue strength
. Increases ultimate tensile strength
. Decreases abrasive wear
. Decreases oxidation resistance without remelting
. Increases elongation to failure

Correct Answer & Explanation

. Decreases abrasive wear


Explanation

Highly cross-linked polyethylene significantly decreases abrasive and adhesive wear rates in total joint arthroplasty. However, it concomitantly decreases mechanical properties such as fatigue strength, ultimate tensile strength, and elongation to failure.

Question 1725

Topic: Biomechanics & Biomaterials

A physical therapist applies a constant load to a patient's contracted Achilles tendon, resulting in a gradual increase in tendon length over time. This phenomenon is a demonstration of which viscoelastic property?

. Stress relaxation
. Hysteresis
. Creep
. Fatigue failure
. Isotropic deformation

Correct Answer & Explanation

. Creep


Explanation

Creep is the time-dependent deformation (increase in strain) of a viscoelastic tissue when subjected to a constant load (stress). Stress relaxation, conversely, is the decrease in stress over time when the tissue is held at a constant length.

Question 1726

Topic: Biomechanics & Biomaterials

In total hip arthroplasty, the use of highly cross-linked polyethylene (HXLPE) has significantly reduced wear rates compared to conventional polyethylene. What is the primary mechanical trade-off associated with increasing the radiation dose to increase cross-linking?

. Decreased ultimate tensile strength and fatigue crack propagation resistance
. Increased oxidation rate in vivo without remelting
. Decreased volumetric wear
. Increased generation of submicron particles per unit of wear
. Decreased elastic modulus leading to rapid rim failure

Correct Answer & Explanation

. Decreased ultimate tensile strength and fatigue crack propagation resistance


Explanation

Highly cross-linked polyethylene drastically reduces adhesive and abrasive wear. However, the cross-linking process (via irradiation) compromises the material's mechanical properties, specifically reducing its ultimate tensile strength, elongation to failure, and fatigue crack propagation resistance. This makes it more susceptible to fatigue-related failures such as rim cracking if malaligned.

Question 1727

Topic: Biomechanics & Biomaterials

A new orthopedic implant material is being biomechanically tested. The total area under the stress-strain curve up to the point of fracture represents which of the following material properties?

. Toughness
. Yield strength
. Elastic modulus
. Ductility
. Brittleness

Correct Answer & Explanation

. Toughness


Explanation

The total area under the stress-strain curve from zero strain to the point of failure (fracture) represents the material's toughness, which is the amount of energy absorbed before fracture. Yield strength is the stress at which plastic deformation begins. Elastic modulus is the slope of the linear (elastic) portion. Ductility is the amount of plastic strain before failure.

Question 1728

Topic: Biomechanics & Biomaterials

During a revision open reduction and internal fixation of a nonunion, a surgeon uses a stainless steel screw through a titanium alloy plate. Several months later, rapid degradation is noted at the screw-plate interface. This is primarily an example of which type of corrosion?

. Crevice corrosion
. Fretting corrosion
. Galvanic corrosion
. Pitting corrosion
. Intergranular corrosion

Correct Answer & Explanation

. Galvanic corrosion


Explanation

Galvanic corrosion occurs when two dissimilar metals with different anodic indices are placed in electrical contact within a conductive fluid (such as body fluid). The less noble metal becomes the anode and corrodes at an accelerated rate.

Question 1729

Topic: Biomechanics & Biomaterials

In orthopedic biomechanics, when a constant load is applied to a viscoelastic tissue such as a ligament or tendon over an extended period, the tissue will slowly continue to elongate. This time-dependent deformation is known as:

. Stress relaxation
. Creep
. Hysteresis
. Fatigue failure
. Anisotropy

Correct Answer & Explanation

. Creep


Explanation

Creep is the progressive time-dependent deformation (strain) of a viscoelastic material when subjected to a constant load (stress). Stress relaxation, conversely, is the decrease in stress over time when the material is held at a constant strain/deformation.

Question 1730

Topic: Biomechanics & Biomaterials
To reduce wear rates in total joint arthroplasty, ultra-high-molecular-weight polyethylene (UHMWPE) undergoes irradiation to become highly cross-linked. While cross-linking successfully decreases volumetric wear, what is the primary mechanical disadvantage of this process?
. Increased rate of in vivo oxidation over time
. Decreased ultimate tensile strength and reduced fatigue crack propagation resistance
. Increased generation of biologically active wear debris leading to severe osteolysis
. Decreased biocompatibility leading to metal hypersensitivity
. Increased cold flow (creep) deformation under static loads

Correct Answer & Explanation

. Decreased ultimate tensile strength and reduced fatigue crack propagation resistance


Explanation

Highly cross-linking UHMWPE (via gamma or electron beam irradiation) dramatically reduces its wear rate. However, the trade-off is a reduction in mechanical properties, specifically decreased ultimate tensile strength, yield strength, ductility, and resistance to fatigue crack propagation. Oxidation is mitigated by remelting or adding antioxidants like Vitamin E.

Question 1731

Topic: Biomechanics & Biomaterials

During ACL reconstruction rehabilitation, what biomechanical property is responsible for the gradual elongation of a tendon graft over time when subjected to a constant continuous load?

. Stress relaxation
. Creep
. Hysteresis
. Fatigue failure
. Viscoelasticity

Correct Answer & Explanation

. Creep


Explanation

Creep is the progressive deformation (elongation) of a viscoelastic material when subjected to a constant load over time. Stress relaxation is the decrease in stress over time under a constant deformation.

Question 1732

Topic: Biomechanics & Biomaterials

A patient with a stainless steel dynamic compression plate subsequently has a titanium screw inserted into the plate. What type of corrosion is most likely to occur at the screw-plate interface?

. Fretting corrosion
. Crevice corrosion
. Galvanic corrosion
. Pitting corrosion
. Intergranular corrosion

Correct Answer & Explanation

. Galvanic corrosion


Explanation

Galvanic corrosion occurs when two dissimilar metals (e.g., stainless steel and titanium) are in physical contact within a conductive fluid (body fluid). The less noble metal acts as an anode and corrodes.

Question 1733

Topic: Biomechanics & Biomaterials

Which of the following modifications to a cortical screw will most significantly increase its pullout strength in diaphyseal bone?

. Increasing the outer diameter
. Increasing the inner (core) diameter
. Increasing the thread pitch
. Decreasing the thread density
. Decreasing the outer diameter

Correct Answer & Explanation

. Increasing the outer diameter


Explanation

Screw pullout strength is most significantly increased by increasing the outer diameter. Decreasing the inner core diameter also increases pullout strength but severely reduces the screw's resistance to fatigue failure.

Question 1734

Topic: Biomechanics & Biomaterials

Which type of corrosion occurs primarily when a stainless steel screw is used in direct mechanical combination with a titanium plate in an orthopedic construct?

. Fretting corrosion
. Crevice corrosion
. Galvanic corrosion
. Pitting corrosion
. Intergranular corrosion

Correct Answer & Explanation

. Galvanic corrosion


Explanation

Galvanic corrosion occurs when two dissimilar metals are in direct contact within an electrolytic fluid medium, creating an electrochemical potential difference. Mixing titanium and stainless steel implants should generally be avoided to prevent this.

Question 1735

Topic: Biomechanics & Biomaterials

A 19-year-old female collegiate soccer player sustains a noncontact twisting injury to her knee, resulting in an ACL tear. Which of the following factors is considered the most significant modifiable contributor to the higher incidence of ACL tears in female athletes compared to males?

. Intercondylar notch width
. Hormonal fluctuations during the menstrual cycle
. Increased Q-angle and valgus alignment
. Neuromuscular control and landing biomechanics
. Generalized ligamentous laxity

Correct Answer & Explanation

. Neuromuscular control and landing biomechanics


Explanation

Correct Answer: DWhile anatomic (notch width, Q-angle) and hormonal factors have been implicated in the higher rate of ACL tears in females, neuromuscular factors (such as landing biomechanics, decreased hamstring-to-quadriceps strength ratio, and altered muscle activation patterns) are considered the most significant and, importantly, modifiable risk factors. Neuromuscular training programs have been shown to effectively reduce the incidence of ACL tears in female athletes.

Question 1736

Topic: Biomechanics & Biomaterials

When preparing an articulating polymethylmethacrylate (PMMA) antibiotic spacer for a two-stage revision of an infected total knee arthroplasty, which specific characteristic of the chosen antibiotic is most crucial to ensure effective local elution and efficacy?

. High thermal lability to dissolve quickly in the joint.
. A strictly bacteriostatic rather than bactericidal mechanism of action.
. Availability in a fine powder form and high thermostability.
. A high systemic toxicity profile to ensure local potency.
. Rapid degradation at body temperature (37°C).

Correct Answer & Explanation

. Availability in a fine powder form and high thermostability.


Explanation

Antibiotics mixed into PMMA bone cement must be thermostable to withstand the high exothermic temperatures of the curing process without losing efficacy. They must also be in a powder form (not liquid) to allow uniform mixing and proper elution from the cement mantle (e.g., vancomycin, tobramycin).

Question 1737

Topic: Biomechanics & Biomaterials

Regarding the surgical treatment of a large, symptomatic chondromyxoid fibroma of the proximal tibia in a young adult, what is the most appropriate definitive management?

. Observation with serial radiographs
. Simple intralesional curettage without adjuvants
. Extended intralesional curettage with high-speed burring and grafting
. Wide en bloc resection and endoprosthetic reconstruction
. Primary radiation therapy

Correct Answer & Explanation

. Extended intralesional curettage with high-speed burring and grafting


Explanation

Chondromyxoid fibroma has a high recurrence rate (up to 25%) if treated with simple curettage alone. Extended intralesional curettage with a high-speed burr and local adjuvants (phenol, cryotherapy) followed by grafting or PMMA is the standard of care.

Question 1738

Topic: Biomechanics & Biomaterials

A 55-year-old male presents with severe acute monoarticular pain, erythema, and swelling in his first metatarsophalangeal joint. Joint aspiration reveals negatively birefringent, needle-shaped crystals under polarized light microscopy. Which of the following is the composition of these crystals?

. Calcium pyrophosphate dihydrate
. Basic calcium phosphate
. Monosodium urate
. Hydroxyapatite
. Cholesterol

Correct Answer & Explanation

. Monosodium urate


Explanation

The patient has an acute attack of gout. Gout is characterized by the deposition of monosodium urate crystals in the joint space, which appear as needle-shaped and negatively birefringent under polarized light microscopy.

Question 1739

Topic: Biomechanics & Biomaterials

A 9-year-old boy with a history of juvenile dermatomyositis presents with hard, painful nodules under the skin over his elbows and knees.

What is the primary composition of these deposits?

. Monosodium urate
. Calcium pyrophosphate dihydrate
. Calcium hydroxyapatite
. Cholesterol crystals
. Amyloid fibrils

Correct Answer & Explanation

. Calcium hydroxyapatite


Explanation

The image demonstrates calcinosis cutis, a frequent and debilitating complication of juvenile dermatomyositis. The dystrophic deposits are primarily composed of calcium hydroxyapatite.

Question 1740

Topic: Biomechanics & Biomaterials

A 10-year-old girl with a history of juvenile dermatomyositis develops widespread, firm subcutaneous nodules around her elbows, knees, and pelvis. Some of these nodules have ulcerated and express a chalky white substance.

What is the primary mineral composition of these deposits?

. Monosodium urate
. Calcium pyrophosphate dihydrate
. Calcium hydroxyapatite
. Basic calcium phosphate
. Cholesterol crystals

Correct Answer & Explanation

. Calcium hydroxyapatite


Explanation

The patient has calcinosis universalis, a common late complication of juvenile dermatomyositis (affecting up to 40% of cases). The nodules are composed of calcium hydroxyapatite deposits in the skin and fascial planes.