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Question 761

Topic: Biomechanics & Biomaterials

Radiographic evaluation of a patient 2 years after an uncemented total hip arthroplasty shows proximal femoral bone resorption. This phenomenon, known as stress shielding, can be minimized by selecting a stem material with an elastic modulus closer to that of cortical bone. Which of the following solid metals best fits this description?

. Cobalt-chromium alloy
. Titanium alloy (Ti-6Al-4V)
. 316L Stainless steel
. Alumina ceramic
. Polymethylmethacrylate (PMMA)

Correct Answer & Explanation

. Cobalt-chromium alloy


Explanation

Titanium alloy has an elastic modulus of approximately 110 GPa, which is much closer to cortical bone (15-20 GPa) than cobalt-chromium (220 GPa) or stainless steel (200 GPa). A closer modulus match reduces stress shielding.

Question 762

Topic: Biomechanics & Biomaterials

Articular cartilage exhibits complex biphasic viscoelastic behavior. Under rapid, heavy compressive loading, the initial resistance to deformation is primarily provided by:

. The tensile properties of Type II collagen
. The low permeability of the matrix and interstitial fluid pressurization
. The osmotic swelling pressure of chondrocytes
. The rapid flow of interstitial fluid out of the matrix
. The elastic recoil of hyaluronic acid molecules

Correct Answer & Explanation

. The tensile properties of Type II collagen


Explanation

In the biphasic theory of cartilage biomechanics, initial resistance to compressive loads is due to fluid pressurization within the tissue. The extremely low permeability of the solid matrix traps the fluid, bearing the majority of the applied load.

Question 763

Topic: Biomechanics & Biomaterials

An intramedullary nail is used to stabilize a transverse midshaft femur fracture. If the surgeon chooses to ream the canal and insert a solid nail with a diameter of 12 mm instead of 10 mm, the torsional rigidity of the nail increases by approximately what factor?

. 1.20
. 1.44
. 2.07
. 2.98
. 4.00

Correct Answer & Explanation

. 1.20


Explanation

Torsional rigidity of a solid cylinder is proportional to the polar moment of inertia, which scales with the radius (or diameter) to the fourth power. The ratio is (12/10)^4 = (1.2)^4, which equals approximately 2.07.

Question 764

Topic: Biomechanics & Biomaterials

A diaphyseal tibia fracture is treated with rigid plate fixation. According to the principles of stress shielding, which material property of the plate most heavily dictates the degree of osteopenia that will occur underneath the plate?

. Yield strength
. Ultimate tensile strength
. Modulus of elasticity
. Ductility
. Fatigue limit

Correct Answer & Explanation

. Yield strength


Explanation

The modulus of elasticity (Young's modulus) dictates the stiffness of the material. Implants with a higher modulus of elasticity (e.g., stainless steel) bear more of the physiologic load, leading to stress shielding and subsequent osteopenia in the underlying bone.

Question 765

Topic: Biomechanics & Biomaterials

Articular cartilage exhibits distinct viscoelastic properties during weight-bearing. Which of the following biomechanical phenomena describes the progressive deformation of cartilage over time when subjected to a constant static load?

. Hysteresis
. Stress relaxation
. Creep
. Isotropism
. Plasticity

Correct Answer & Explanation

. Hysteresis


Explanation

Creep is a viscoelastic property defined as the progressive deformation of a material over time under a constant load. Stress relaxation, conversely, is the decrease in stress over time when the material is held at a constant deformation.

Question 766

Topic: Biomechanics & Biomaterials

When a normal flexor tendon is subjected to tensile loading, the initial "toe region" of its load-elongation curve corresponds to which microstructural event?

. Microfailure of individual collagen fibrils
. Plastic deformation of the extracellular matrix
. Elastic deformation of tropocollagen cross-links
. Uncrimping of the crimped collagen fibers
. Macroscopic tendon tearing

Correct Answer & Explanation

. Microfailure of individual collagen fibrils


Explanation

The toe region of a tendon's stress-strain curve represents the uncrimping (straightening) of the resting crimp pattern of collagen fibers. It occurs under low stress and allows flexibility before the tendon engages its stiffer linear region.

Question 767

Topic: Biomechanics & Biomaterials

Cortical bone exhibits vastly different mechanical properties (e.g., strength and stiffness) depending on the direction of the applied load. This fundamental material property is best described as:

. Viscoelasticity
. Isotropy
. Anisotropy
. Piezoelectricity
. Biphasic behavior

Correct Answer & Explanation

. Viscoelasticity


Explanation

Anisotropy refers to a material having different mechanical properties depending on the direction of the applied force. Cortical bone is highly anisotropic, being strongest in longitudinal compression and weakest in transverse tension.

Question 768

Topic: Biomechanics & Biomaterials

To reduce wear in total joint arthroplasty, ultra-high-molecular-weight polyethylene (UHMWPE) is often highly cross-linked using gamma or electron beam irradiation. What subsequent manufacturing step is essential to prevent long-term oxidative degradation of the implant?

. Sterilization in an oxygen-rich environment
. Coating the polyethylene with hydroxyapatite
. Remelting or annealing to eliminate free radicals
. Quenching in cold saline
. Etymol oxide gas sterilization

Correct Answer & Explanation

. Sterilization in an oxygen-rich environment


Explanation

Irradiation generates free radicals within the polyethylene structure. To prevent these free radicals from reacting with oxygen in vivo (which causes oxidation and embrittlement), the polyethylene is either remelted or annealed to extinguish residual free radicals.

Question 769

Topic: Biomechanics & Biomaterials

When utilizing a solid cylindrical intramedullary nail for diaphyseal fracture fixation, the torsional rigidity of the implant is proportional to its radius raised to which power?

. 1
. 2
. 3
. 4
. 5

Correct Answer & Explanation

. 1


Explanation

The torsional rigidity of a solid cylinder is determined by its polar moment of inertia (J = ฯ€ยทrโด / 2). Therefore, torsional rigidity is proportional to the radius to the fourth power, making minor increases in nail diameter exponentially stiffer.

Question 770

Topic: Biomechanics & Biomaterials

Polymethylmethacrylate (PMMA) bone cement provides immediate fixation of total joint arthroplasty components. By which of the following mechanisms does PMMA secure the implant to the surrounding host bone?

. Covalent chemical bonding to the bony trabeculae
. Osteointegration at the cement-bone interface
. Interlocking micro-mechanical fixation
. Galvanic adhesion
. Direct binding to type I collagen

Correct Answer & Explanation

. Covalent chemical bonding to the bony trabeculae


Explanation

PMMA is not an adhesive and does not chemically bond to bone. It functions as a grout, providing rigid fixation via interlocking micro-mechanical fixation as it permeates the cancellous bone trabeculae before polymerizing.

Question 771

Topic: Biomechanics & Biomaterials

During the physiological loading of a normal ligament, the initial non-linear "toe region" of the stress-strain curve represents which of the following microstructural events?

. Failure of the weakest collagen fibrils
. Viscoelastic stress relaxation
. Micro-tearing of cross-links
. Uncrimping of collagen fibers
. Fluid exudation from the extracellular matrix

Correct Answer & Explanation

. Failure of the weakest collagen fibrils


Explanation

The "toe region" represents the initial phase of the stress-strain curve where minimal force results in significant elongation. This corresponds microscopically to the straightening or "uncrimping" of the naturally crimped collagen fibers.

Question 772

Topic: Biomechanics & Biomaterials

Mixing stainless steel and titanium implants in the same surgical field can lead to accelerated degradation of the implants. Which of the following best describes the primary mechanism of this process?

. Abrasive wear
. Fretting corrosion
. Galvanic corrosion
. Crevice corrosion
. Fatigue failure

Correct Answer & Explanation

. Abrasive wear


Explanation

Galvanic corrosion occurs when two dissimilar metals are placed in physical contact within a conductive fluid (such as body fluids). This creates an electrochemical cell, leading to accelerated corrosion of the less noble metal.

Question 773

Topic: Biomechanics & Biomaterials

Because bone is a viscoelastic material, its mechanical properties depend heavily on the rate of loading. When cortical bone is subjected to a high strain rate (fast loading), how do its properties change compared to low strain rate loading?

. It becomes more ductile and absorbs less energy
. It becomes stiffer and fails at a higher ultimate load
. It experiences greater stress relaxation
. Its yield point decreases significantly
. It exhibits increased plastic deformation before failure

Correct Answer & Explanation

. It becomes more ductile and absorbs less energy


Explanation

Due to its viscoelastic nature, bone loaded at high strain rates becomes stiffer, sustains higher ultimate loads before failure, and absorbs more energy (higher area under the stress-strain curve) compared to slow loading rates.

Question 774

Topic: Biomechanics & Biomaterials

Which of the following wear mechanisms is defined as the removal of material resulting from two articulating surfaces rubbing against each other, leading to local microscopic welding and subsequent tearing off of particles?

. Abrasive wear
. Adhesive wear
. Third-body wear
. Fretting wear
. Corrosive wear

Correct Answer & Explanation

. Abrasive wear


Explanation

Adhesive wear occurs when two surfaces slide against each other, causing local asperities to bond or "weld" together. Subsequent movement tears these micro-welds apart, releasing wear debris.

Question 775

Topic: Biomechanics & Biomaterials

Which of the following common orthopaedic biomaterials possesses the highest modulus of elasticity (stiffness)?

. Polymethylmethacrylate (PMMA)
. Cortical bone
. Titanium alloy (Ti-6Al-4V)
. 316L Stainless steel
. Cobalt-chromium (Co-Cr) alloy

Correct Answer & Explanation

. Polymethylmethacrylate (PMMA)


Explanation

Cobalt-chromium has the highest modulus of elasticity (~220-240 GPa), making it the stiffest among standard implant materials. Stainless steel is ~200 GPa, Titanium alloy is ~110 GPa, and cortical bone is ~15-20 GPa.

Question 776

Topic: Biomechanics & Biomaterials

Which of the following mechanical properties is determined by the slope of the linear elastic region of a stress-strain curve?

. Toughness
. Yield strength
. Young's modulus
. Ultimate tensile strength
. Creep

Correct Answer & Explanation

. Toughness


Explanation

Young's modulus (elastic modulus) is the measure of the intrinsic stiffness of a material. It is defined mathematically as the slope of the stress-strain curve in the elastic (linear) region.

Question 777

Topic: Biomechanics & Biomaterials

When designing a solid intramedullary nail, doubling the radius of the nail will increase its torsional rigidity by a factor of:

. 2
. 4
. 8
. 16
. 32

Correct Answer & Explanation

. 2


Explanation

For a solid cylinder, torsional rigidity is proportional to the polar moment of inertia, which scales with the radius to the fourth power (r^4). Therefore, doubling the radius increases the torsional rigidity by 2^4, which is 16.

Question 778

Topic: Biomechanics & Biomaterials

A tendon graft used for ACL reconstruction is tensioned to a specific length and fixed in place. Over time, the tension in the graft progressively decreases while the length remains constant. This viscoelastic property is known as:

. Creep
. Hysteresis
. Stress relaxation
. Fatigue failure
. Strain rate dependency

Correct Answer & Explanation

. Creep


Explanation

Stress relaxation is the time-dependent decrease in stress (tension) under a constant strain (length). In contrast, creep is a time-dependent increase in strain under a constant stress.

Question 779

Topic: Biomechanics & Biomaterials

A surgeon uses a stainless steel screw with a titanium plate for fracture fixation. Which of the following is the most likely consequence of using these mixed metals in vivo?

. Crevice corrosion
. Fretting corrosion
. Galvanic corrosion
. Pitting corrosion
. Fatigue failure

Correct Answer & Explanation

. Crevice corrosion


Explanation

Galvanic corrosion occurs when two dissimilar metals with different electrochemical potentials are placed in contact within a conductive fluid (such as body fluids). This leads to accelerated corrosion of the more anodic metal.

Question 780

Topic: Biomechanics & Biomaterials

Cortical bone is stronger in compression along its longitudinal axis than it is when subjected to transverse loading. This material property, where mechanical behavior depends on the direction of loading, is known as:

. Viscoelasticity
. Isotropism
. Anisotropy
. Plasticity
. Hysteresis

Correct Answer & Explanation

. Viscoelasticity


Explanation

Anisotropy is the property of a material exhibiting different mechanical properties depending on the direction of the applied load. Bone is highly anisotropic due to the longitudinal orientation of osteons.